Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952389 | 0.85 | SLC2A1 (0.34) | IMPDH2 | |
| SCHEMBL9952270 | 0.77 | REN (0.31) | — | |
| SCHEMBL17138393 | 0.76 | NPC1 (0.31) | — | |
| SCHEMBL9952278 | 0.71 | ALDH1A1 (0.38) | IMPDH2 | |
| SCHEMBL28712872 | 0.70 | ALDH1A1 (0.44) | IMPDH2 | |
| SCHEMBL9952656 | 0.66 | IMPDH2 (0.34) | IMPDH2 | |
| SCHEMBL9953206 | 0.66 | IMPDH2 (0.34) | IMPDH2 | |
| SCHEMBL9952084 | 0.65 | LMNA (0.38) | IMPDH2 | |
| SCHEMBL9952238 | 0.65 | ADRB2 (0.36) | IMPDH2 | |
| SCHEMBL9952391 | 0.62 | SLC2A1 (0.34) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |