SCHEMBL10046226

SCHEMBL10046226

CC(C)C(=O)[C@H](N)CCCCN

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.59
GNAI3 P08754 1/20 0.46
GNAO1 P09471 1/20 0.46
GNAI1 P63096 1/20 0.46
DPP7 Q9UHL4 8/20 0.42
DPP8 Q6V1X1 4/20 0.42
DPP9 Q86TI2 4/20 0.42
RNPEP Q9H4A4 1/20 0.42
DPP4 P27487 2/20 0.41
CPB2 Q96IY4 4/20 0.38
TRPV1 Q8NER1 1/20 0.38
TRPA1 O75762 1/20 0.38
FAP Q12884 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13337173 1.00 GSR (0.59) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL10046228 1.00 GSR (0.59) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL20383848 0.98 GSR (0.57) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL20388836 0.98 GSR (0.57) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL13429506 0.98 GSR (0.57) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL23762407 0.98 GSR (0.57) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL12280588 0.93 GSR (0.50) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL12278737 0.93 GSR (0.50) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL17173859 0.93 GSR (0.50) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL4761845 0.84 GABRR1 (0.46) GSRDPP7DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911412-B2 Derivatized chitosan polymers and methods of treating vascular disorders SYNEDGEN, INC. (US) 2024-02-27 US disclosed
US-11786547-B2 Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds SYNEDGEN, INC. (US) 2023-10-17 US disclosed
US-11786547-B2 Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds SYNEDGEN, INC. (US) 2023-10-17 US disclosed
US-11717532-B2 Methods and compositions for treating wounds utilizing chitosan compounds SYNEDGEN, INC. (US) 2023-08-08 US disclosed
US-11717532-B2 Methods and compositions for treating wounds utilizing chitosan compounds SYNEDGEN, INC. (US) 2023-08-08 US disclosed
WO-2022174179-A9 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2023-02-02 WO disclosed
US-20230021050-A1 COMPOSITIONS AND METHODS OF THEIR USE SYNEDGEN, INC. 2023-01-19 US disclosed
US-11433092-B2 Compositions and methods of use for wound healing SYNEDGEN, INC. (US) 2022-09-06 US disclosed
US-20220160754-A1 DERIVATIZED CHITOSAN POLYMERS AND METHODS OF TREATING VASCULAR DISORDERS SYNEDGEN, INC. 2022-05-26 US disclosed
US-11331331-B2 N4-hydroxycytidine and derivatives and anti-viral uses related thereto EMORY UNIVERSITY (US) 2022-05-17 US disclosed
US-20120329751-A1 METHODS AND COMPOSITIONS FOR DISRUPTING BIOFILM UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS UNITED STATES GOVERNMENT 2012-12-27 US disclosed
US-20120301408-A1 ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS UNITED STATES GOVERNMENT 2012-11-29 US disclosed
US-20120301408-A1 ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS UNITED STATES GOVERNMENT 2012-11-29 US disclosed
US-8119780-B2 Chitosan-derivative compounds and methods of controlling microbial populations SYNEDGEN, INC. (US) 2012-02-21 US disclosed
US-8119780-B2 Chitosan-derivative compounds and methods of controlling microbial populations SYNEDGEN, INC. (US) 2012-02-21 US disclosed
WO-2011028968-A1 ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS SYNEDGEN, INC. (US) 2011-03-10 WO disclosed
WO-2010056927-A1 CHITOSAN DERIVATIVES ALONE OR IN COMBINATION FOR THE TREATMENT OF MDR MICROBIAL INFECTIONS SYNEDGEN, INC. (US) 2010-05-20 WO disclosed
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria SHIONOGI & CO., LTD. (JP) 2008-04-24 US disclosed
US-20070281904-A1 Chitosan-derivative compounds and methods of controlling microbial populations UNITED STATES GOVERNMENT 2007-12-06 US disclosed
US-20070281904-A1 Chitosan-derivative compounds and methods of controlling microbial populations UNITED STATES GOVERNMENT 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11433092-B2 Compositions and methods of use for wound healing PARG, ARGLU1, AREG GSR 3366/4885GNAI3 1127/4885GNAO1 1350/4885
US-11331331-B2 N4-hydroxycytidine and derivatives and anti-viral uses related thereto ENTPD1, NME2, NME1 GSR 2887/4885GNAI3 2512/4885GNAO1 332/4885
US-20220160754-A1 DERIVATIZED CHITOSAN POLYMERS AND METHODS OF TREATING VASCULAR DISORDERS CHIA, CHI3L1, CHI3L2 GSR 322/4885GNAI3 3119/4885GNAO1 2677/4885
US-20230021050-A1 COMPOSITIONS AND METHODS OF THEIR USE ARG1, ARG2, FUT6 GSR 286/4885GNAI3 1399/4885GNAO1 1639/4885
US-20070281904-A1 Chitosan-derivative compounds and methods of controlling microbial populations ARG1, NRDC, CHIA GSR 1727/4885GNAI3 2109/4885GNAO1 2306/4885
US-20120329751-A1 METHODS AND COMPOSITIONS FOR DISRUPTING BIOFILM UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS CHIT1, ALG1, CSGALNACT1 GSR 2761/4885GNAI3 1835/4885GNAO1 1832/4885
US-20120301408-A1 ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS CHIT1, ALG1, SI GSR 1899/4885GNAI3 3903/4885GNAO1 3117/4885
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria CSGALNACT1, MON2, NR2C2 GSR 2449/4885GNAI3 2996/4885GNAO1 1420/4885
US-11717532-B2 Methods and compositions for treating wounds utilizing chitosan compounds CHIA, MMP8, CHIT1 GSR 2485/4885GNAI3 3143/4885GNAO1 3506/4885
US-11786547-B2 Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds CHIT1, ALG1, CSGALNACT1 GSR 2761/4885GNAI3 1835/4885GNAO1 1832/4885
US-11911412-B2 Derivatized chitosan polymers and methods of treating vascular disorders CHIA, CHI3L1, CHI3L2 GSR 322/4885GNAI3 3119/4885GNAO1 2677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.