SCHEMBL1005894

SCHEMBL1005894

Nc1cccc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.59
ATM Q13315 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
MAPT P10636 4/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
ALDH1A1 P00352 4/20 0.55
CASP1 P29466 2/20 0.55
ALOX15 P16050 1/20 0.55
CASP7 P55210 1/20 0.55
HPGD P15428 2/20 0.43
HTT P42858 2/20 0.43
MAPK1 P28482 1/20 0.43
HBB P68871 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ADRA2C P18825 1/20 0.43
CYP3A4 P08684 1/20 0.42
RECQL P46063 1/20 0.42
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29829630 1.00 KDM4E (0.59) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL29789020 1.00 KDM4E (0.59) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL21446203 0.89 KDM4E (0.52) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL25686447 0.87 MAPT (0.51) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL57391 0.85 L3MBTL1 (0.73) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL29351958 0.85 L3MBTL1 (0.73) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL29371952 0.85 L3MBTL1 (0.73) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL28074214 0.84 ALDH1A1 (0.55) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL24725937 0.84 MAPT (0.44) KDM4EATML3MBTL1MAPTMEN1
Aniline SCHEMBL21142138 0.83 L3MBTL1 (0.78) KDM4EATML3MBTL1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108003165-B A kind of synthetic method of 5,11- dihydro -5- Phenylindole simultaneously [3,2-b] carbazole 河南省科学院化学研究所有限公司 2019-09-13 CN claimed
CN-108003165-A A kind of synthetic method of 5,11- dihydros -5- Phenylindoles simultaneously [3,2-b] carbazole 河南省科学院化学研究所有限公司 2018-05-08 CN claimed
US-20230320198-A1 COMPOUND AND APPLICATION THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-10-05 US disclosed
US-20230320198-A1 COMPOUND AND APPLICATION THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-10-05 US disclosed
US-20230269958-A1 ORGANIC COMPOUND, AND ELECTRONIC COMPONENT AND ELECTRONIC DEVICE HAVING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-24 US disclosed
US-20230269958-A1 ORGANIC COMPOUND, AND ELECTRONIC COMPONENT AND ELECTRONIC DEVICE HAVING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-24 US disclosed
US-20230219981-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20230219981-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20230219981-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20230189638-A1 ORGANIC COMPOUND AND ELECTRONIC DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-20230189638-A1 ORGANIC COMPOUND AND ELECTRONIC DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
CN-102471677-A Compounds for luminescent applications DU PONT 2012-05-23 CN disclosed
EP-2449054-A2 CHRYSENE COMPOUNDS FOR LUMINESCENT APPLICATIONS E. I. du Pont de Nemours and Company (US) 2012-05-09 EP disclosed
US-20120104371-A1 Phosphorescent Compound and Organic Electroluminescent Device Using the Same LG DISPLAY CO., LTD. 2012-05-03 US disclosed
US-20120104371-A1 Phosphorescent Compound and Organic Electroluminescent Device Using the Same LG DISPLAY CO., LTD. 2012-05-03 US disclosed
EP-2367900-A2 ANTHRACENE COMPOUNDS FOR LUMINESCENT APPLICATIONS E. I. du Pont de Nemours and Company (US) 2011-09-28 EP disclosed
WO-2011002870-A2 CHRYSENE COMPOUNDS FOR LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-01-06 WO disclosed
US-20100187508-A1 ANTHRACENE COMPOUNDS FOR LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 US disclosed
WO-2010071871-A2 ANTHRACENE COMPOUNDS FOR LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 WO disclosed
CN-101326165-A M-carbazolyl phenyl compounds HODOGAYA CHEMICAL CO LTD (JP) 2008-12-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230269958-A1 ORGANIC COMPOUND, AND ELECTRONIC COMPONENT AND ELECTRONIC DEVICE HAVING SAME ORC3, PIEZO1, OR10J3 KDM4E 1128/4885ATM 1331/4885L3MBTL1 2276/4885
US-20230219981-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME ELP1, NFE2L2, LEF1 KDM4E 1209/4885ATM 4282/4885L3MBTL1 186/4885
US-20230189638-A1 ORGANIC COMPOUND AND ELECTRONIC DEVICE AND ELECTRONIC APPARATUS THEREOF AOX1, PIEZO1, CYP2E1 KDM4E 2157/4885ATM 2438/4885L3MBTL1 3874/4885
US-20100187508-A1 ANTHRACENE COMPOUNDS FOR LUMINESCENT APPLICATIONS ANXA2, ANXA1, ANXA3 KDM4E 2114/4885ATM 235/4885L3MBTL1 2013/4885
US-20230320198-A1 COMPOUND AND APPLICATION THEREOF TRPA1, TRPV5, TRPM5 KDM4E 2421/4885ATM 4190/4885L3MBTL1 1681/4885
US-20120104371-A1 Phosphorescent Compound and Organic Electroluminescent Device Using the Same PTH1R, PGLS, PPIP5K2 KDM4E 3639/4885ATM 2438/4885L3MBTL1 3871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.