Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | PDE4A | P27815 | 4/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 3/20 | 0.42 |
| ▸ | PDE1A | P54750 | 3/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109779 | 0.89 | ACHE (0.53) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3302064 | 0.87 | MAPT (0.52) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20362610 | 0.82 | MAPT (0.47) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10882757 | 0.82 | MAPT (0.47) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13067787 | 0.82 | ACHE (0.64) | ACHEMAPTCYP3A4KMT2AMEN1 | |
| SCHEMBL14462083 | 0.81 | ACHE (0.44) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18124422 | 0.80 | ACHE (0.43) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13096060 | 0.80 | ACHE (0.61) | ACHEMAPTCYP3A4KMT2AMEN1 | |
| SCHEMBL643649 | 0.80 | CYP1A2 (0.62) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2621002 | 0.80 | ERN1 (0.50) | ACHEPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180221303-A1 | PERITONEAL THERAPEUTIC FLUID | OPTERION HEALTH AG (CH) | 2018-08-09 | — | — | US | disclosed |
| US-20180214387-A1 | AQUEOUS SOLUTION COMPRISING A POLYPHENOL | OPTERION HEALTH AG (CH) | 2018-08-02 | — | — | US | disclosed |
| US-9139574-B2 | Tumor targeted drug combretastatin A4 derivative | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2015-09-22 | — | — | US | disclosed |
| US-20140128384-A1 | TUMOR TARGETED DRUG COMBRETASTATIN A4 DERIVATIVE | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2014-05-08 | — | — | US | disclosed |
| US-20130310332-A1 | MAPLE TREE-DERIVED PRODUCTS AND USES THEREOF | UNIVERSITY OF RHODE ISLAND (US) | 2013-11-21 | — | — | US | disclosed |
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | Zhejiang Wild Wind Pharmaceutical Co., Ltd. (CN) | 2012-02-23 | — | — | US | disclosed |
| US-7902330-B2 | Protein kinase inhibitors and methods for identifying same | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-03-08 | — | — | US | disclosed |
| US-7892701-B2 | Fuel cell | KABUSHIKI KAISHA TOSHIBA (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20100216055-A1 | FUEL CELL | ARIMURA TOMOAKI | 2010-08-26 | — | — | US | disclosed |
| US-20100055524-A1 | FUEL CELL | KABUSHIKI KAISHA TOSHIBA (JP) | 2010-03-04 | — | — | US | disclosed |
| WO-2007134828-A1 | PYRAZOLO [3, 4-D] PYRIMIDINE DERIVATIVES USEFUL TO TREAT RESPIRATORY DISORDERS | NOVARTIS AG (CH) | 2007-11-29 | — | — | WO | disclosed |
| US-20070254312-A1 | Protein Kinase Inhibitors and Methods for Identiying Same | NATIONAL INSTITUTES OF HEALTH | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254312-A1 | Protein Kinase Inhibitors and Methods for Identiying Same | PRKCA, PRKCE, PRKCB | ACHE 3098/4885PDE4A 501/4885PDE4B 618/4885 |
| US-20180214387-A1 | AQUEOUS SOLUTION COMPRISING A POLYPHENOL | SORD, AQP1, SI | ACHE 1824/4885PDE4A 4292/4885PDE4B 4111/4885 |
| US-20140128384-A1 | TUMOR TARGETED DRUG COMBRETASTATIN A4 DERIVATIVE | TUBA4A, TUBGCP4, TUBB4A | ACHE 4449/4885PDE4A 262/4885PDE4B 228/4885 |
| US-20180221303-A1 | PERITONEAL THERAPEUTIC FLUID | FABP6, ALB, FABP2 | ACHE 2132/4885PDE4A 3046/4885PDE4B 3067/4885 |
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | TUBB1, TUBB, TUBB3 | ACHE 3380/4885PDE4A 3810/4885PDE4B 3849/4885 |
| US-20130310332-A1 | MAPLE TREE-DERIVED PRODUCTS AND USES THEREOF | FASN, NNT, MAPK7 | ACHE 449/4885PDE4A 3645/4885PDE4B 3048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.