Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.36 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19185801 | 0.80 | NQO1 (0.33) | CA1CA9KDM4EMAPTNQO1 | |
| SCHEMBL547874 | 0.80 | MAPT (0.35) | ALDH1A1SMN1; SMN2CA1POLBCA2 | |
| SCHEMBL14506378 | 0.77 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2CA1POLBCA2 | |
| SCHEMBL22693489 | 0.77 | CYP1A1 (0.40) | ALDH1A1CA1CA9KDM4ECYP1A2 | |
| SCHEMBL820796 | 0.77 | L3MBTL1 (0.48) | ALDH1A1SMN1; SMN2CA1POLBCA2 | |
| SCHEMBL21720746 | 0.75 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2CA1POLBCA2 | |
| SCHEMBL21720739 | 0.75 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2CA1POLBCA2 | |
| SCHEMBL21720688 | 0.75 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2CA1POLBCA2 | |
| SCHEMBL20843941 | 0.75 | NQO1 (0.39) | ALDH1A1SMN1; SMN2CA1POLBCA2 | |
| SCHEMBL15307453 | 0.75 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2CA1POLBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-08-01 | — | — | US | disclosed |
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-11155567-B2 | Sting agonist compounds and methods of use | MERSANA THERAPEUTICS, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-20210032269-A1 | STING AGONIST COMPOUNDS AND METHODS OF USE | MERSANA THERAPEUTICS, INC. | 2021-02-04 | — | — | US | disclosed |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-02-13 | — | — | US | disclosed |
| US-10334851-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2019-07-02 | — | — | US | disclosed |
| US-20190127354-A1 | 2,4,6,7-TETRASUBSTITUTED QUINOLINE COMPOUNDS AS INHIBITORS OF DNA METHYLTRANSFERASES | FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA (ES) | 2019-05-02 | — | — | US | disclosed |
| US-10196356-B2 | Mixed disulfide conjugates of thienopyridine compounds and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-02-05 | — | — | US | disclosed |
| US-20180155289-A1 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-06-07 | — | — | US | disclosed |
| US-9902703-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2018-02-27 | — | — | US | disclosed |
| US-20120208790-A1 | ION CHANNEL MODULATORS AND METHODS OF USE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-08-16 | — | — | US | disclosed |
| US-8193194-B2 | Ion channel modulators and methods of use | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-05 | — | — | US | disclosed |
| US-20110136874-A1 | FUNGICIDAL N-(2-PYRIDYLPROPYL) CARBOXAMIDE DERIVATIVES AND THEIR OXA, AZA AND THIA ANALOGUES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-06-09 | — | — | US | disclosed |
| US-20110136874-A1 | FUNGICIDAL N-(2-PYRIDYLPROPYL) CARBOXAMIDE DERIVATIVES AND THEIR OXA, AZA AND THIA ANALOGUES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-06-09 | — | — | US | disclosed |
| US-7932283-B2 | Fungicide N-cyclopropyl-sulfonylamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| US-20100010048-A1 | Fungicide 2-pyridyl-methylene-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| US-20080293737-A1 | ION CHANNEL MODULATORS AND METHODS OF USE | VERTEX PHARMACEUTICALS INCORPORATED | 2008-11-27 | — | — | US | disclosed |
| WO-2007113327-A2 | FUNGICIDE N-CYCLOPROPYL-SULFONYLAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | ALDH1A1 2674/4885SMN1; SMN2 1844/4885CA1 1909/4885 |
| US-10334851-B2 | Herbicidal isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | ALDH1A1 292/4885SMN1; SMN2 4074/4885CA1 1882/4885 |
| US-10196356-B2 | Mixed disulfide conjugates of thienopyridine compounds and uses thereof | TST, TXN, TXNRD2 | ALDH1A1 218/4885SMN1; SMN2 1272/4885CA1 3057/4885 |
| US-20120208790-A1 | ION CHANNEL MODULATORS AND METHODS OF USE | CACNA1G, CACNA1C, CACNA1B | ALDH1A1 3359/4885SMN1; SMN2 1767/4885CA1 916/4885 |
| US-11155567-B2 | Sting agonist compounds and methods of use | STING1, IRF3, MAVS | ALDH1A1 4848/4885SMN1; SMN2 2815/4885CA1 4862/4885 |
| US-20080293737-A1 | ION CHANNEL MODULATORS AND METHODS OF USE | CACNA1G, CACNA1C, CACNA1B | ALDH1A1 3359/4885SMN1; SMN2 1767/4885CA1 916/4885 |
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CYP4X1, PDXK | ALDH1A1 894/4885SMN1; SMN2 3624/4885CA1 4296/4885 |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CYP4X1, PDXK | ALDH1A1 894/4885SMN1; SMN2 3624/4885CA1 4296/4885 |
| US-20190127354-A1 | 2,4,6,7-TETRASUBSTITUTED QUINOLINE COMPOUNDS AS INHIBITORS OF DNA METHYLTRANSFERASES | DNMT3B, DNMT1, DNMT3A | ALDH1A1 308/4885SMN1; SMN2 2894/4885CA1 4657/4885 |
| US-20110136874-A1 | FUNGICIDAL N-(2-PYRIDYLPROPYL) CARBOXAMIDE DERIVATIVES AND THEIR OXA, AZA AND THIA ANALOGUES | PNPO, AZI2, CYP51A1 | ALDH1A1 1811/4885SMN1; SMN2 3390/4885CA1 4064/4885 |
| US-20180155289-A1 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF | TST, TXN, TXNRD2 | ALDH1A1 218/4885SMN1; SMN2 1272/4885CA1 3057/4885 |
| US-20210032269-A1 | STING AGONIST COMPOUNDS AND METHODS OF USE | STING1, IRF3, MAVS | ALDH1A1 4848/4885SMN1; SMN2 2815/4885CA1 4862/4885 |
| US-20100010048-A1 | Fungicide 2-pyridyl-methylene-carboxamide derivatives | CYP51A1, ME2, ME3 | ALDH1A1 1267/4885SMN1; SMN2 2716/4885CA1 3106/4885 |
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | AAAS, PROC, AADAC | ALDH1A1 2104/4885SMN1; SMN2 4177/4885CA1 3881/4885 |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | CYP51A1, ERG28, CBR3 | ALDH1A1 2140/4885SMN1; SMN2 2319/4885CA1 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.