SCHEMBL1023047

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11130896	0.83	TSHR (0.56)	TSHRLMNAKDM4EKMT2AALDH1A1
	SCHEMBL1023544	0.79	FFAR3 (0.41)	TSHRLMNAALDH1A1
	SCHEMBL11134833	0.77	TSHR (0.59)	TSHRLMNAKDM4EKMT2AALDH1A1
	SCHEMBL11136461	0.75	TSHR (0.56)	TSHRLMNAKDM4EKMT2AALDH1A1
	Lithium Ion SCHEMBL28398952	0.74	TSHR (0.50)	TSHRLMNAKDM4EKMT2AALDH1A1
	SCHEMBL1022943	0.74	CA1 (0.32)	LMNA
	SCHEMBL30617931	0.74	TSHR (0.62)	TSHRLMNAKDM4EKMT2AALDH1A1
	SCHEMBL2064945	0.73	TSHR (0.54)	TSHRLMNAKDM4EKMT2AALDH1A1
	SCHEMBL6739129	0.73	CES2 (0.48)	TSHRLMNAKMT2AALDH1A1HSD17B10
	SCHEMBL11130894	0.72	TSHR (0.59)	TSHRLMNAKDM4EKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.