Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 8/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Delparantag SCHEMBL19445838 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| Delparantag SCHEMBL10261851 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| Delparantag SCHEMBL19445836 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| Delparantag SCHEMBL10267622 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| SCHEMBL15138936 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| Delparantag SCHEMBL31024631 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| Delparantag SCHEMBL10262676 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| SCHEMBL19945112 | 0.99 | ERAP2 (0.46) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| SCHEMBL21371608 | 0.99 | ERAP2 (0.46) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| SCHEMBL10261754 | 0.99 | ERAP2 (0.46) | ERAP2LNPEPERAP1SUV39H2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025118719-A1 | SMALL MOLECULE HEPARIN REVERSAL AGENT WITH TRIAZINE SKELETON, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2025-06-12 | — | — | WO | disclosed |
| US-20240398853-A1 | MULTIVALENT POLYCATION INHIBITION OF POLYANIONS IN BLOOD | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-12-05 | — | — | US | disclosed |
| EP-4404965-A1 | MULTIVALENT POLYCATION INHIBITION OF POLYANIONS IN BLOOD | The Regents Of The University Of Michigan (US) | 2024-07-31 | — | — | EP | disclosed |
| CN-117624137-A | Triazine skeleton small molecule heparin reversal agent and preparation method and application thereof | 中国药科大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-117417328-A | Triazine compound for reversing anticoagulant activity of low-molecular heparin, and preparation method and application thereof | 中国药科大学 | 2024-01-19 | — | — | CN | disclosed |
| US-20230310435-A1 | HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | INNOVATION PHARMACEUTICALS INC. (US) | 2023-10-05 | — | — | US | disclosed |
| US-20230310435-A1 | HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | INNOVATION PHARMACEUTICALS INC. (US) | 2023-10-05 | — | — | US | disclosed |
| US-20230302139-A1 | TARGETED RNA DEGRADATION ALLOWS PRECISION REPURPOSING OF PROTEIN-TARGETED SMALL MOLECULE MEDICINES TO RNA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-09-28 | — | — | US | disclosed |
| US-11666571-B2 | Host defense protein (HDP) mimetics for prophylaxis and/or treatment of inflammatory diseases of the gastrointestinal tract | INNOVATION PHARMACEUTICALS INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11666571-B2 | Host defense protein (HDP) mimetics for prophylaxis and/or treatment of inflammatory diseases of the gastrointestinal tract | INNOVATION PHARMACEUTICALS INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-8354556-B2 | Processes for preparing a polymeric compound | POLYMEDIX, INC. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120295922-A1 | Compounds For Use In Treatment Of Mucositis | POLYMEDIX, INC. (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2012158672-A2 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | POLYMEDIX, INC. (US) | 2012-11-22 | — | — | WO | disclosed |
| US-20120258141-A9 | Methods Of Immune Modulation | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-10-11 | — | — | US | disclosed |
| US-20120039945-A1 | Methods Of Immune Modulation | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2012006315-A2 | METHODS OF IMMUNE MODULATION | POLYMEDIX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20110178104-A1 | Anti-Heparin Compounds | POLYMEDIX INC. (US) | 2011-07-21 | — | — | US | disclosed |
| WO-2011084970-A1 | ANTI-HEPARIN COMPOUNDS | POLYMEDIX INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20110098498-A1 | Processes For Preparing A Polymeric Compound | POLYMEDIX, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| WO-2011050162-A1 | PROCESSES FOR PREPARING A POLYMERIC COMPOUND | POLYMEDIX, INC. (US) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098498-A1 | Processes For Preparing A Polymeric Compound | F12, ALG1, ABCB11 | ERAP2 3200/4885LNPEP 965/4885ERAP1 2586/4885 |
| US-20120295922-A1 | Compounds For Use In Treatment Of Mucositis | MUC1, FUT6, MMP8 | ERAP2 646/4885LNPEP 1252/4885ERAP1 1190/4885 |
| US-20230302139-A1 | TARGETED RNA DEGRADATION ALLOWS PRECISION REPURPOSING OF PROTEIN-TARGETED SMALL MOLECULE MEDICINES TO RNA | METTL16, AGO2, RBM26 | ERAP2 2294/4885LNPEP 2284/4885ERAP1 937/4885 |
| US-11666571-B2 | Host defense protein (HDP) mimetics for prophylaxis and/or treatment of inflammatory diseases of the gastrointestinal tract | FABP2, HMGB1, MASP2 | ERAP2 100/4885LNPEP 40/4885ERAP1 121/4885 |
| US-20120258141-A9 | Methods Of Immune Modulation | IFNG, CD14, TLR3 | ERAP2 1201/4885LNPEP 922/4885ERAP1 1521/4885 |
| US-20120039945-A1 | Methods Of Immune Modulation | IFNG, CD14, TLR3 | ERAP2 1201/4885LNPEP 922/4885ERAP1 1521/4885 |
| US-20110178104-A1 | Anti-Heparin Compounds | SERPINC1, CFH, SERPINH1 | ERAP2 325/4885LNPEP 222/4885ERAP1 332/4885 |
| US-20240398853-A1 | MULTIVALENT POLYCATION INHIBITION OF POLYANIONS IN BLOOD | SERPINC1, FGB, F7 | ERAP2 1891/4885LNPEP 117/4885ERAP1 1619/4885 |
| US-20230310435-A1 | HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | FABP2, HMGB1, MASP2 | ERAP2 100/4885LNPEP 40/4885ERAP1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.