Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.47 |
| ▸ | SMPD3 | Q9NY59 | 12/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577231 | 0.92 | AMY1A (0.55) | AMY1ASMPD3NOX1 | |
| SCHEMBL10576075 | 0.89 | ALOX5 (0.47) | AMY1AMAPT | |
| SCHEMBL10576840 | 0.86 | HDAC6 (0.36) | TP53MAPT | |
| SCHEMBL10574269 | 0.85 | NPC1 (0.48) | TP53MAPT | |
| SCHEMBL10577324 | 0.84 | DGAT1 (0.46) | TP53MAPT | |
| SCHEMBL10580104 | 0.83 | PDE5A (0.45) | AMY1A | |
| SCHEMBL10574912 | 0.83 | MITF (0.37) | TP53MAPT | |
| SCHEMBL10580688 | 0.82 | HDAC6 (0.52) | TP53MAPT | |
| SCHEMBL10578441 | 0.82 | HDAC6 (0.46) | TP53MAPT | |
| SCHEMBL10574083 | 0.81 | LOXL2 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |