SCHEMBL1126798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126783	0.74	RAB9A (0.42)	THRBLMNASMN1; SMN2HTTMMP1
	SCHEMBL1127303	0.72	CHRNB2 (0.50)	LMNASMN1; SMN2ALDH1A1MAPTMEN1
	SCHEMBL1126750	0.69	GAA (0.37)	SMN1; SMN2ALDH1A1MAPTL3MBTL1
	SCHEMBL1992161	0.68	MAPT (0.44)	LMNAHTTALDH1A1MAPTL3MBTL1
	SCHEMBL1127233	0.67	MEN1 (0.50)	LMNASMN1; SMN2HTTALDH1A1MAPT
	SCHEMBL1126812	0.67	ALDH1A1 (0.48)	LMNASMN1; SMN2HTTALDH1A1L3MBTL1
	SCHEMBL1988597	0.67	IL2 (0.41)	LMNASMN1; SMN2ALDH1A1MAPT
	SCHEMBL1127002	0.67	AR (0.40)	ARLMNAALDH1A1MAPTMEN1
	SCHEMBL1126560	0.67	SIGMAR1 (0.40)	LMNAALDH1A1MAPTMEN1KMT2A
	SCHEMBL1126468	0.67	TSHR (0.39)	LMNASMN1; SMN2ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.