Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.44 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.36 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 2/20 | 0.37 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GLB1 | P16278 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482391 | 0.89 | THRB (0.38) | THRBMAPK1ALDH1A1CYP3A4HPGD | |
| SCHEMBL16259538 | 0.81 | L3MBTL1 (0.42) | ALDH1A1HPGDTSHRL3MBTL1CA12 | |
| SCHEMBL7786711 | 0.80 | NR4A1 (0.34) | THRBCYP3A4HPGDTSHRNR4A1 | |
| SCHEMBL21364354 | 0.80 | LDHA (0.56) | HSD17B10L3MBTL1CA12CA1CA2 | |
| SCHEMBL13877943 | 0.80 | TTR (0.46) | ALDH1A1ALOX15HSD17B10L3MBTL1LDHA | |
| SCHEMBL11333090 | 0.79 | TTR (0.44) | ALDH1A1ALOX15HSD17B10L3MBTL1LDHA | |
| SCHEMBL11483062 | 0.79 | TTR (0.44) | THRBALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL67965 | 0.77 | HSD11B1 (0.46) | CYP3A4HPGDTSHRPKLRL3MBTL1 | |
| SCHEMBL29615335 | 0.77 | HSD11B1 (0.46) | CYP3A4HPGDTSHRPKLRL3MBTL1 | |
| SCHEMBL30130401 | 0.77 | HSD11B1 (0.46) | CYP3A4HPGDTSHRPKLRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104621170-A | Acetamiprid and emamectin benzoate mixed soluble granular insecticide and preparation method thereof | HEBEI VEYONG BIO CHEM CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-104621170-A | Acetamiprid and emamectin benzoate mixed soluble granular insecticide and preparation method thereof | HEBEI VEYONG BIO CHEM CO LTD | 2015-05-20 | — | — | CN | disclosed |
| US-4252556-A | CATIONIC MORPHOLINIUM, PYRIDINIUM, QUINOLINIUM SURFACTANTS | NOVEX TALALMANYFEJLESZTO ES ERTEKESITO KULKERESKEDELMI RT. (HU) | 1981-02-24 | — | — | US | disclosed |
| US-4252555-A | IMIDAZOLINIUM CATIONIC SURFACTANT | NOVEX TALALMANYFEJLESZTO ES ERTEKESITO KULKERESKEDELMI RT. (HU) | 1981-02-24 | — | — | US | disclosed |
| US-4218234-A | CATIONIC COMPOUNDS | NOVEX RT. (HU) | 1980-08-19 | — | — | US | disclosed |