Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253621 | 0.84 | — | — | |
| SCHEMBL7450444 | 0.78 | LMNA (0.33) | — | |
| SCHEMBL575194 | 0.74 | — | — | |
| SCHEMBL18235521 | 0.74 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL35767 | 0.73 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL30393703 | 0.73 | CA2 (0.36) | — | |
| SCHEMBL3346640 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL2231830 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL575332 | 0.72 | — | — | |
| SCHEMBL12604843 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9180111-B2 | Reduction in complement activation and inflammation during tissue injury by carotenoids, carotenoid analogs, or derivatives thereof | CARDAX PHARMA, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-8063101-B2 | Carotenoid analogs and derivatives for the prevention of platelet aggregation | CARDAX PHARMACEUTICALS, INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20090124574-A1 | Carotenoid analogs and derivatives for the prevention of platelet aggregation | CARDAX PHARMA, INC. | 2009-05-14 | — | — | US | disclosed |
| US-20080293679-A1 | Use of carotenoids and/or carotenoid derivatives/analogs for reduction/inhibition of certain negative effects of COX inhibitors | CARDAX PHARMACEUTICALS, INC. | 2008-11-27 | — | — | US | disclosed |
| US-7435861-B2 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | CARDAX PHARMACEUTICALS, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-20080221377-A1 | Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates | CARDAX PHARMACEUTICALS, INC. | 2008-09-11 | — | — | US | disclosed |
| US-7320997-B2 | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-20070015735-A1 | Water-dispersible carotenoids, including analogs and derivatives | LOCKWOOD SAMUEL F | 2007-01-18 | — | — | US | disclosed |
| US-3963437-A | Flame retardant process for cellulosic material including cyanamide, phosphonic acid, antimony oxide and polymeric halogen-containing material | COTTON INCORPORATED (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015735-A1 | Water-dispersible carotenoids, including analogs and derivatives | NQO1, NOS1, AQP1 | ALDH1A1 1495/4885 |
| US-20080221377-A1 | Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates | HCCS, SQOR, CBR3 | ALDH1A1 1671/4885 |
| US-20080293679-A1 | Use of carotenoids and/or carotenoid derivatives/analogs for reduction/inhibition of certain negative effects of COX inhibitors | LPL, ALOX12, LCLAT1 | ALDH1A1 1668/4885 |
| US-20090124574-A1 | Carotenoid analogs and derivatives for the prevention of platelet aggregation | PROC, PFKP, PF4 | ALDH1A1 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.