SCHEMBL12092172

SCHEMBL12092172

CCCOCCC(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
DGKA P23743 1/20 0.32
HSD17B10 Q99714 1/20 0.31
EPHX2 P34913 1/20 0.31
CTSK P43235 1/20 0.31
CYP2D6 P10635 1/20 0.31
TLR2 O60603 1/20 0.31
TLR1 Q15399 1/20 0.31
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26418533 0.98 STING1 (0.34) STING1ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL25695697 0.98 STING1 (0.34) STING1ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL15697678 0.98 STING1 (0.34) STING1ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL19532911 0.98 STING1 (0.34) STING1ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL14728292 0.98 STING1 (0.34) STING1ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL19532910 0.98 STING1 (0.34) STING1ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL13573633 0.98 STING1 (0.34) STING1ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL12660493 0.98 STING1 (0.34) STING1ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL12906508 0.98 STING1 (0.34) STING1ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL18843243 0.89 STING1 (0.37) STING1HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117460737-A Heteroaromatic compounds, method for the production and use thereof 四川科伦博泰生物医药股份有限公司 2024-01-26 CN disclosed
US-11731960-B2 Biheterocyclic compound Sumitomo Pharma Co., Ltd. (JP) 2023-08-22 US disclosed
US-20230158010-A1 LUMINALLY-ACTING N-(PIPERIDIN-4-YL)BENZAMIDE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-25 US disclosed
US-20230149550-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2023-05-18 US disclosed
CN-108148153-B Solid catalyst and method for preparing propylene polymer or copolymer using the same 韩华道达尔有限公司 2021-08-10 CN disclosed
US-10808048-B2 Process of manufacture of catalyst and propylene polymer that use this or copolymer for propylene polymerization HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2020-10-20 US disclosed
EP-3683243-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION Hanwha Total Petrochemical Co., Ltd. (KR) 2020-07-22 EP disclosed
US-20180186931-A1 HETERO TYPE MONODISPERSED POLYETHYLENE GLYCOL, INTERMEDIATE FOR PRODUCTION OF HETERO TYPE MONODISPERSED POLYETHYLENE GLYCOL, METHODS FOR PRODUCING SAME, AND HETERO TYPE MONODISPERSED POLYETHYLENE GLYCOL CONJUGATE TOHOKU TECHNO ARCH CO., LTD. (JP) 2018-07-05 US disclosed
US-20180155461-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-07 US disclosed
EP-3330299-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION Hanwha Total Petrochemical Co., Ltd. (KR) 2018-06-06 EP disclosed
US-9493413-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2016-11-15 US disclosed
US-9481829-B2 Compound, haze-lowering agent, liquid crystal composition, polymer material, and film FUJIFILM CORPORATION (JP) 2016-11-01 US disclosed
US-20150322155-A1 ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE Sushou M-conj Biotech Co., Ltd (CN) 2015-11-12 US disclosed
US-8952147-B2 Conjugates, preparation thereof, and therapeutic use thereof SANOFI (FR) 2015-02-10 US disclosed
US-20140155590-A1 Conjugates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents SANOFI SA (FR) 2014-06-05 US disclosed
US-20140138580-A1 COMPOUND, HAZE-LOWERING AGENT, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL, AND FILM FUJIFILM CORPORATION (JP) 2014-05-22 US disclosed
EP-2274279-B1 NITRIC OXIDE DONATING PROSTAMIDES NICOX SA (FR) 2013-07-31 EP disclosed
US-8481042-B2 Conjugates of pyrrolo[1,4]benzodiazepine dimers as anticancer agents SANOFI (FR) 2013-07-09 US disclosed
US-20120244172-A1 Conjudates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents SANOFI (FR) 2012-09-27 US disclosed
US-20120225089-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120225089-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF ERG28, CARS1, FOLH1 STING1 2211/4885ALDH1A1 1912/4885HDAC3 1814/4885
US-20230149550-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE DMPK, DTYMK, MYCBP STING1 1893/4885ALDH1A1 4368/4885HDAC3 1221/4885
US-11731960-B2 Biheterocyclic compound NR4A3, NGF, OGFR STING1 1998/4885ALDH1A1 3217/4885HDAC3 552/4885
US-20230158010-A1 LUMINALLY-ACTING N-(PIPERIDIN-4-YL)BENZAMIDE DERIVATIVES HTR4, HTR1A, HTR1D STING1 3387/4885ALDH1A1 1147/4885HDAC3 1342/4885
US-20120244172-A1 Conjudates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents GABRA4, GABRA1, GABRA2 STING1 4376/4885ALDH1A1 908/4885HDAC3 464/4885
US-20140155590-A1 Conjugates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents GABRA4, GABRP, GABRA1 STING1 4683/4885ALDH1A1 476/4885HDAC3 293/4885
US-20150322155-A1 ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE DCLRE1A, AADAC, UACA STING1 3977/4885ALDH1A1 952/4885HDAC3 700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.