SCHEMBL12372721

SCHEMBL12372721

c1ccc(-c2ccc(-c3ccc(N(c4ccc(-c5cccc6c5oc5ccccc56)cc4)c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)s2)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.39
▸ APP P05067 1/20 0.35
▸ PRKDC P78527 5/20 0.35
▸ KDM4E B2RXH2 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ GGPS1 O95749 1/20 0.33
▸ PTGES2 Q9H7Z7 1/20 0.32
▸ MAPT P10636 1/20 0.30
▸ PRMT5 O14744 1/20 0.30
▸ WDR77 Q9BQA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19272831 0.95 ALOX5 (0.36) ALOX5APPPRKDCKDM4EATM
SCHEMBL20792827 0.95 ALOX5 (0.37) ALOX5APPPRKDCGGPS1PTGES2
SCHEMBL10306816 0.93 ALOX5 (0.43) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL12372719 0.93 ALOX5 (0.40) ALOX5APPPRKDCKDM4EATM
SCHEMBL24509626 0.93 ALOX5 (0.43) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL10306828 0.93 ALOX5 (0.44) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL10306954 0.93 ALOX5 (0.44) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL10306945 0.93 ALOX5 (0.44) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL12136069 0.92 ALOX5 (0.44) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL10306938 0.92 ALOX5 (0.44) ALOX5PRKDCKDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048237-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-23 — — US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 — — US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 — — US disclosed
EP-3816175-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-07-17 — — EP disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 — — US disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 — — US disclosed
US-12035613-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 — — US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 — — US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 — — US disclosed
US-12035614-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 — — US disclosed
US-20160240799-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-18 — — US disclosed
EP-3056504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-08-17 — — EP disclosed
US-20160233436-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 — — US disclosed
US-20160233436-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 — — US disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 — — US disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 — — US disclosed
US-7998596-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-08-16 — — US disclosed
US-7998596-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-08-16 — — US disclosed
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 — — US disclosed
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND ALOX5 2064/4885APP 1693/4885PRKDC 3338/4885
US-20160233436-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, OPRD1 ALOX5 868/4885APP 4278/4885PRKDC 3020/4885
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, SBDS, OCIAD2 ALOX5 66/4885APP 2140/4885PRKDC 4731/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 ALOX5 247/4885APP 2254/4885PRKDC 3589/4885
US-12048237-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP ALOX5 271/4885APP 2982/4885PRKDC 3838/4885
US-20160233429-A1 Organic Electroluminescent Materials and Devices NBAS, TBCB, SLC1A2 ALOX5 2050/4885APP 515/4885PRKDC 4717/4885
US-12035614-B2 Organic electroluminescent materials and devices ZFR, SOD1, NDUFS2 ALOX5 2906/4885APP 4170/4885PRKDC 1986/4885
US-20160240799-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP2 ALOX5 906/4885APP 2825/4885PRKDC 4521/4885
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME DDC, TYR, EML4 ALOX5 3073/4885APP 770/4885PRKDC 1491/4885
US-12035613-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC ALOX5 721/4885APP 2795/4885PRKDC 2018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback