Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28501418 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL30480947 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL563975 | 0.77 | POLB (0.47) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL11510900 | 0.77 | CYP2A6 (0.44) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL1965079 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL28495219 | 0.74 | BCAT2 (0.44) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL1256220 | 0.74 | GPR84 (0.43) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL30729584 | 0.74 | ACP3 (0.47) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL11770352 | 0.74 | GPR84 (0.43) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL3646058 | 0.72 | CA2 (0.46) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732895-B1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| CN-102548981-B | N1-acyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC | 2015-05-13 | — | — | CN | disclosed |
| CN-101977900-B | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2013-11-27 | — | — | CN | disclosed |
| CN-102056915-A | 2-alkynyl-6-pyridin-2-yl-pyridazinones, 2-alkynyl-6-pyridin-2-yl-dihydropyridazinones, 2-alkynyl-6-pyrimidin-2-yl-pyridazinones and 2-alkynyl-6-pyrimidin-2-yl-dihydropyridazinones and their use as fungicides | DOW AGROSCIENCES LLC | 2011-05-11 | — | — | CN | disclosed |
| US-7935826-B2 | Insecticidal N-substituted (heteroaryl)cycloalkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2011-05-03 | — | — | US | disclosed |
| US-20110039904-A1 | Alcohol alkoxylates, agents comprising the same and use of the alcohol alkoxylates as adjuvants in the agrochemical field | BASF SE (DE) | 2011-02-17 | — | — | US | disclosed |
| CN-101977900-A | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2011-02-16 | — | — | CN | disclosed |
| US-20100210461-A1 | Compositions comprising alcohol alkoxylates, and use of the alcohol alkoxylates as adjuvant for the agrochemical sector | BASF SE (DE) | 2010-08-19 | — | — | US | disclosed |
| US-20100184603-A1 | Alcohol alkoxylates, compositions containing these, and use of the alcohol alkoxylates as adjuvants for the agrochemical field | BASF SE (DE) | 2010-07-22 | — | — | US | disclosed |
| US-7678920-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-03-16 | — | — | US | disclosed |
| US-20100004290-A1 | INSECTICIDAL N-SUBSTITUTED (HETEROARYL)CYCLOALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-01-07 | — | — | US | disclosed |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | CORTEVA AGRISCIENCE LLC | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210461-A1 | Compositions comprising alcohol alkoxylates, and use of the alcohol alkoxylates as adjuvant for the agrochemical sector | ACOX3, PAOX, HAO2 | ALDH1A1 983/4885HSD17B10 400/4885HPGD 1160/4885 |
| US-20110039904-A1 | Alcohol alkoxylates, agents comprising the same and use of the alcohol alkoxylates as adjuvants in the agrochemical field | CHRM1, CHRM2, AP2M1 | ALDH1A1 389/4885HSD17B10 1275/4885HPGD 2060/4885 |
| US-20100004290-A1 | INSECTICIDAL N-SUBSTITUTED (HETEROARYL)CYCLOALKYL SULFOXIMINES | DDT, MSL1, STS | ALDH1A1 3453/4885HSD17B10 1247/4885HPGD 3468/4885 |
| US-20100184603-A1 | Alcohol alkoxylates, compositions containing these, and use of the alcohol alkoxylates as adjuvants for the agrochemical field | ACOX3, PAOX, ADH5 | ALDH1A1 930/4885HSD17B10 801/4885HPGD 1939/4885 |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | GSS, STS, SMS | ALDH1A1 3325/4885HSD17B10 1587/4885HPGD 2521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.