SCHEMBL127607

SCHEMBL127607

NC(=O)c1cc(O)ccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
CA12 O43570 2/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA7 P43166 2/20 0.59
CA9 Q16790 2/20 0.59
CA14 Q9ULX7 2/20 0.59
ALOX5 P09917 1/20 0.59
PTGS2 P35354 1/20 0.59
TSHR P16473 1/20 0.59
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 2/20 0.50
POLB P06746 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PTPN1 P18031 2/20 0.46
MYC P01106 1/20 0.46
MAPT P10636 3/20 0.45
ESR2 Q92731 3/20 0.45
CYP3A4 P08684 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30297923 1.00 ALDH1A1 (0.59) ALDH1A1CA12CA1CA2CA7
SCHEMBL591760 0.91 ALDH1A1 (0.59) ALDH1A1CA12CA1CA2CA7
SCHEMBL1805264 0.89 CES2 (0.50) ALDH1A1CA12CA1CA2CA7
SCHEMBL31298798 0.86 ALDH1A1 (0.70) ALDH1A1CA12CA1CA2CA7
SCHEMBL177949 0.86 ALDH1A1 (0.70) ALDH1A1CA12CA1CA2CA7
SCHEMBL31390818 0.84 ALDH1A1 (0.67) ALDH1A1CA12CA1CA2CA7
Hydrochloric Acid SCHEMBL11161670 0.84 ALDH1A1 (0.67) ALDH1A1CA12CA1CA2CA7
Ammonia Solution, Strong SCHEMBL28482629 0.84 ALDH1A1 (0.67) ALDH1A1CA12CA1CA2CA7
Ammonia Solution, Strong SCHEMBL28482626 0.84 ALDH1A1 (0.67) ALDH1A1CA12CA1CA2CA7
SCHEMBL28480927 0.84 ALDH1A1 (0.67) ALDH1A1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220339088-A1 METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE USE OF AN ORGANIC C1-C6 ALKOXY SILANE AND AN ACIDIFIER HENKEL AG & CO. KGAA (DE) 2022-10-27 US claimed
EP-4031104-A1 METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE USE OF AN ORGANIC C1-C8-ALKOXY SILANE AND AN ACIDIFIER Henkel AG & Co. KGaA (DE) 2022-07-27 EP claimed
CN-114449997-A Involving the use of C1-C6Process for colouring keratin materials with an organoalkoxysilane and an acidifying agent 汉高股份有限及两合公司 2022-05-06 CN claimed
WO-2021052722-A1 METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE USE OF AN ORGANIC C1-C6 ALKOXY SILANE AND AN ACIDIFIER HENKEL AG & CO. KGAA (DE) 2021-03-25 WO claimed
US-20170151156-A1 HAIR TREATMENT AGENTS HENKEL AG & CO. KGAA (DE) 2017-06-01 US claimed
US-20170151146-A1 HAIR TREATMENT AGENTS HENKEL AG & CO. KGAA (DE) 2017-06-01 US claimed
US-20170151147-A1 HIGH-PERFORMANCE HAIR TREATMENT AGENT WITH ANTI-WASH-OUT EFFECT HENKEL AG & CO. KGAA (DE) 2017-06-01 US claimed
EP-1326577-B1 NOVEL USE OF SHORT-CHAINED CARBOXYLIC ACIDS HENKEL AG & CO KGAA (DE) 2008-10-15 EP claimed
EP-1326579-B1 NOVEL USE OF SHORT-CHAINED CARBOXYLIC ACIDS HENKEL KGAA (DE) 2008-02-13 EP claimed
US-20050249784-A1 Preparations containing diformates and short-chain carboxylic acids BASF AKTIENGESELLSCHAFT (DE) 2005-11-10 US claimed
US-12485077-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, an effect pigment and a post-treatment agent HENKEL AG & CO. KGAA (DE) 2025-12-02 US disclosed
US-12364261-B2 Liquid sulfonylurea- and Li-salt containing herbicidal compositions BATTELLE UK LIMITED (GB) 2025-07-22 US disclosed
US-12357549-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound, a sealing reagent, and a pre-treatment agent HENKEL AG & CO. KGAA (DE) 2025-07-15 US disclosed
US-12357554-B2 Process of coloring keratinous material comprising the use of an organosilicon compound, an effect pigment, and a sealing reagent VI HENKEL AG & CO. KGAA (DE) 2025-07-15 US disclosed
US-12329849-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound, a sealing reagent, and a polymer-containing post-treatment agent HENKEL AG & CO. KGAA (DE) 2025-06-17 US disclosed
WO-2002032383-A2 NOVEL USE OF SHORT-CHAINED CARBOXYLIC ACIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-04-25 WO disclosed
WO-2001097755-A2 VITAMIN B6 DERIVATIVES AS PROTECTIVE COMPONENTS IN THE OXIDATIVE TREATMENT OF HAIR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO disclosed
WO-2001097757-A2 AGENT FOR DYEING OR COLORING AND SIMULTANEOUSLY PROTECTING HAIR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO disclosed
WO-2001097760-A1 STRUCTURE-IMPROVING HAIR CARE AGENTS CONTAINING VITAMIN B6 AND DERIVATIVES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO disclosed
WO-2001097756-A2 NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170151147-A1 HIGH-PERFORMANCE HAIR TREATMENT AGENT WITH ANTI-WASH-OUT EFFECT CD99, TPH2, TPH1 ALDH1A1 575/4885CA12 3270/4885CA1 4657/4885
US-20170151146-A1 HAIR TREATMENT AGENTS OAT, OTC, SLC26A4 ALDH1A1 556/4885CA12 263/4885CA1 707/4885
US-12364261-B2 Liquid sulfonylurea- and Li-salt containing herbicidal compositions LCT, CLIC1, CLIC4 ALDH1A1 2030/4885CA12 170/4885CA1 232/4885
US-12357554-B2 Process of coloring keratinous material comprising the use of an organosilicon compound, an effect pigment, and a sealing reagent VI KRT18, GP6, MSH6 ALDH1A1 826/4885CA12 1514/4885CA1 2028/4885
US-12485077-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, an effect pigment and a post-treatment agent KRT18, KIT, MSH6 ALDH1A1 485/4885CA12 692/4885CA1 815/4885
US-12357549-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound, a sealing reagent, and a pre-treatment agent KRT18, DSG1, PDS5A ALDH1A1 1254/4885CA12 881/4885CA1 1110/4885
US-20220339088-A1 METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE USE OF AN ORGANIC C1-C6 ALKOXY SILANE AND AN ACIDIFIER KRT18, CCNB1, C9 ALDH1A1 47/4885CA12 6/4885CA1 43/4885
US-20170151156-A1 HAIR TREATMENT AGENTS OAT, OTC, SLC26A4 ALDH1A1 556/4885CA12 263/4885CA1 707/4885
US-12329849-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound, a sealing reagent, and a polymer-containing post-treatment agent KRT18, DSG1, PDS5A ALDH1A1 1359/4885CA12 2810/4885CA1 3434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.