Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | CASP3 | P42574 | 3/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29593199 | 1.00 | RAB9A (0.58) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28874458 | 0.85 | ALDH1A1 (0.56) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL2538594 | 0.84 | KDM4E (0.59) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28874293 | 0.81 | L3MBTL1 (0.54) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL29878660 | 0.81 | L3MBTL1 (0.54) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL9105844 | 0.79 | NPC1 (0.61) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL29442076 | 0.79 | NPC1 (0.61) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL903255 | 0.79 | NPC1 (0.61) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| Iodide SCHEMBL8417295 | 0.78 | NPC1 (0.59) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL4454889 | 0.76 | MPO (0.45) | KDM4EMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120059421-A | High-strength regenerated PET composite material and preparation method thereof | 江西绿聚科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-115703737-A | Hydroxypyridones compounds and application thereof as antibiotic sensitizer for overcoming drug resistance of bacterial biofilm | 暨南大学 | 2023-02-17 | — | — | CN | claimed |
| EP-3686203-A1 | 4-SULFUR SUBSTITUTED PODOPHYLLOTOXIN DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | Tang, Yajie (CN) | 2020-07-29 | — | — | EP | claimed |
| CN-111454308-A | Teniposide derivative and preparation method and application thereof | 湖北工业大学 | 2020-07-28 | — | — | CN | claimed |
| US-20200216462-A1 | 4-Sulfur Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof | Tang, YaJie (CN) | 2020-07-09 | — | — | US | claimed |
| US-20200216449-A1 | 4-Sulfur Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof | Tang, YaJie (CN) | 2020-07-09 | — | — | US | claimed |
| CN-108285456-A | 4- sulphur replaces podophyllotoxin derivative and its preparation method and application | 汤亚杰 | 2018-07-17 | — | — | CN | claimed |
| CN-120059421-A | High-strength regenerated PET composite material and preparation method thereof | 江西绿聚科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| US-20250051319-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2025-02-13 | — | — | US | disclosed |
| US-20240409533-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-12-12 | — | — | US | disclosed |
| CN-115703737-B | Hydroxypyridones compound and application thereof as antibiotic sensitizer for overcoming bacterial biomembrane resistance | 暨南大学 | 2024-09-24 | — | — | CN | disclosed |
| US-12071433-B2 | HMOX1 inducers | Astellas Engineered Small Molecules US, Incorporated (US) | 2024-08-27 | — | — | US | disclosed |
| CN-117843579-A | Benzo heterocycle coupled catechol derivative and preparation method and application thereof | 暨南大学 | 2024-04-09 | — | — | CN | disclosed |
| US-5124235-A | Photopolymerization initiator and photosensitive composition employing the same | CANON KABUSHIKI KAISHA (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0453317-A2 | Image forming medium | CANON KABUSHIKI KAISHA (JP) | 1991-10-23 | — | — | EP | disclosed |
| EP-0353030-A2 | Photopolymerization initiator and photosensitive composition employing the same | CANON KABUSHIKI KAISHA (JP) | 1990-01-31 | — | — | EP | disclosed |
| EP-0087701-B1 | PROCESS FOR THE PREPARATION OF 2-CHLOROBENZOXAZOLS | CASSELLA Aktiengesellschaft (DE) | 1986-08-20 | — | — | EP | disclosed |
| US-4517370-A | Process for preparing 2-chlorobenzoxazoles | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-05-14 | — | — | US | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |
| EP-0087701-A2 | Process for the preparation of 2-chlorobenzoxazols | CASSELLA Aktiengesellschaft (DE) | 1983-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051319-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | HDAC6, HDAC9, HDAC1 | RAB9A 75/4885KDM4E 2750/4885NPC1 620/4885 |
| US-20200216462-A1 | 4-Sulfur Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof | WEE1, WEE2, DHFR | RAB9A 3952/4885KDM4E 1474/4885NPC1 4632/4885 |
| US-20200216449-A1 | 4-Sulfur Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof | TPMT, WEE1, DHFR | RAB9A 4217/4885KDM4E 200/4885NPC1 4717/4885 |
| US-20240409533-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | RAB9A 4748/4885KDM4E 2510/4885NPC1 3451/4885 |
| US-12071433-B2 | HMOX1 inducers | HMOX1, HMOX2, HMBS | RAB9A 4725/4885KDM4E 2606/4885NPC1 3292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.