Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357646 | 0.89 | FKBP1A (0.43) | GAASMN1; SMN2KMT2AMEN1FKBP1A | |
| SCHEMBL4364150 | 0.86 | NAAA (0.35) | — | |
| SCHEMBL4351462 | 0.83 | HTR1A (0.40) | KMT2AMEN1 | |
| SCHEMBL13586016 | 0.83 | SMN1; SMN2 (0.43) | GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4355465 | 0.82 | HTR1A (0.35) | — | |
| SCHEMBL4350045 | 0.81 | MCHR1 (0.38) | — | |
| SCHEMBL4351631 | 0.79 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4538463 | 0.78 | NPY2R (0.39) | — | |
| SCHEMBL4356423 | 0.78 | TSHR (0.41) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13586042 | 0.78 | CYP3A4 (0.38) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |