SCHEMBL14028816

SCHEMBL14028816

[N-]=[N+]=Nc1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.54
SMN1; SMN2 Q16637 6/20 0.54
KDM4E B2RXH2 5/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
NPC1 O15118 4/20 0.54
LMNA P02545 4/20 0.54
HTT P42858 4/20 0.54
ALDH1A1 P00352 6/20 0.41
POLB P06746 3/20 0.41
RAB9A P51151 3/20 0.41
CA2 P00918 3/20 0.41
CA12 O43570 2/20 0.41
HSD17B10 Q99714 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALOX15 P16050 2/20 0.41
CA5A P35218 2/20 0.41
CA5B Q9Y2D0 2/20 0.41
HPGD P15428 2/20 0.41
GMNN O75496 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364590 1.00 MAPT (0.54) MAPTSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL30858726 0.82 GABRA1 (0.34) MAPTSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL27630601 0.82 GABRA1 (0.34) MAPTSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL20489081 0.79 G6PD (0.38) MAPTSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL22914960 0.79 TSHR (0.45) MAPTSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL22914956 0.79 LMNA (0.37) MAPTSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL22914949 0.79 TRPA1 (0.45) MAPTSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL23355905 0.75 GABRA1 (0.41) ALDH1A1CA2HSD17B10L3MBTL1CA5A
Hydrogen Sulfide SCHEMBL23355901 0.73 GABRA1 (0.40) F2RPTGS2
SCHEMBL13886922 0.73 APP (0.42) MAPTNPC1POLBRAB9ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121735-B1 SPATIAL-DEPENDENT ANALYSIS OF BIOLOGICAL MATERIAL FROM INTACT TISSUE SAMPLES GENENTECH INC (US) 2025-05-07 EP claimed
CN-119948169-A Bifunctional photocrosslinking probes for covalent capture of intracellular protein-nucleic acid complexes 南加利福尼亚大学 2025-05-06 CN claimed
CN-115943299-A Spatially dependent analysis of biological material from intact tissue samples 基因泰克公司 2023-04-07 CN claimed
EP-4121735-A1 SPATIAL-DEPENDENT ANALYSIS OF BIOLOGICAL MATERIAL FROM INTACT TISSUE SAMPLES GENENTECH, INC. (US) 2023-01-25 EP claimed
US-20210395795-A1 COMPOUND AND A METHOD FOR IDENTIFYING A PROTEIN USING SAID COMPOUND CITY UNIVERSITY OF HONG KONG (HK) 2021-12-23 US claimed
WO-2021188704-A1 SPATIAL-DEPENDENT ANALYSIS OF BIOLOGICAL MATERIAL FROM INTACT TISSUE SAMPLES GENENTECH, INC. (US) 2021-09-23 WO claimed
US-20210226142-A1 UV CROSSLINKING OF PVDF-BASED POLYMERS FOR GATE DIELECTRIC INSULATORS OF ORGANIC THIN-FILM TRANSISTORS CORNING INCORPORATED 2021-07-22 US claimed
CN-110838546-A UV crosslinking of PVDF-based polymers for gate dielectric insulators of organic thin film transistors 康宁股份有限公司 2020-02-25 CN claimed
US-9981923-B2 1,2,3 Triazole antifungal agents and preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-05-29 US claimed
US-20170197924-A1 Novel 1,2,3 Triazole Antifungal Agents and Preparation Thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-07-13 US claimed
CN-106632271-A Erlotinib derivative with antitumor activity, and preparation method and application thereof 河南师范大学 2017-05-10 CN claimed
WO-2015193915-A1 NOVEL 1,2,3 TRIAZOLE ANTIFUNGAL AGENTS AND PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-23 WO claimed
CN-103059010-B Isosorbide-5-Nitrae-benzoxazinone-1,2,3-triazole compound with anti-mycotic activity and preparation method thereof HENAN NORMAL UNIVERSITY (CN) 2015-09-02 CN claimed
US-20260147001-A1 PROTEIN SEQUENCING VIA COUPLING OF POLYMERIZABLE MOLECULES GLYPHIC BIOTECHNOLOGIES, INC. (US) 2026-05-28 US disclosed
US-20260118364-A1 PROTEIN SEQUENCING VIA COUPLING OF POLYMERIZABLE MOLECULES GLYPHIC BIOTECHNOLOGIES INC (US) 2026-04-30 US disclosed
US-12599322-B2 Method for an analyte sensor cover-membrane preparation ROCHE DIABETES CARE, INC. (US) 2026-04-14 US disclosed
US-20080266519-A1 UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS ALCON RESEARCH, LTD. (US) 2008-10-30 US disclosed
CN-101076880-A Method and device for forming monolayer nanostructures and device comprising such monolayer NANOSYS INC (US) 2007-11-21 CN disclosed
CN-1042345-C Gasoline compositions SHELL INT RESEARCH (NL) 1999-03-03 CN disclosed
CN-1083853-A Gasoline composition SHELL INT RESEARCH (NL) 1994-03-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080266519-A1 UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS UACA, CRYZ, CRYAA MAPT 283/4885SMN1; SMN2 4721/4885KDM4E 3758/4885
US-20210395795-A1 COMPOUND AND A METHOD FOR IDENTIFYING A PROTEIN USING SAID COMPOUND DLAT, LYPLA1, QPCTL MAPT 3193/4885SMN1; SMN2 4802/4885KDM4E 155/4885
US-12599322-B2 Method for an analyte sensor cover-membrane preparation F10, S100A10, EPCAM MAPT 1971/4885SMN1; SMN2 802/4885KDM4E 859/4885
US-20260118364-A1 PROTEIN SEQUENCING VIA COUPLING OF POLYMERIZABLE MOLECULES SPPL2B, SPPL2A, MAX MAPT 1215/4885SMN1; SMN2 2180/4885KDM4E 2298/4885
US-20260147001-A1 PROTEIN SEQUENCING VIA COUPLING OF POLYMERIZABLE MOLECULES SPPL2A, SPPL2B, PTMS MAPT 1209/4885SMN1; SMN2 2859/4885KDM4E 2712/4885
US-20170197924-A1 Novel 1,2,3 Triazole Antifungal Agents and Preparation Thereof ERG28, CYP51A1, CYP2F1 MAPT 3813/4885SMN1; SMN2 4432/4885KDM4E 3838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.