Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.37 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.37 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | BAX | Q07812 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898221 | 0.76 | LTA4H (0.45) | LTA4HTSHRCA1CA2CA4 | |
| SCHEMBL187417 | 0.74 | LTA4H (0.43) | LTA4HTSHRCA1CA2CA4 | |
| SCHEMBL29140215 | 0.72 | CA1 (0.43) | LTA4HTSHRCA1CA2CA4 | |
| SCHEMBL1276215 | 0.72 | CA1 (0.43) | LTA4HTSHRCA1CA2CA4 | |
| SCHEMBL14905 | 0.71 | LTA4H (0.60) | LTA4HTSHRCA1CA2CA4 | |
| Boric Acid SCHEMBL10871300 | 0.70 | CA1 (0.41) | LTA4HTSHRCA1CA2CA4 | |
| SCHEMBL1408264 | 0.70 | CA1 (0.41) | LTA4HTSHRCA1CA2CA4 | |
| Potassium Ion SCHEMBL187986 | 0.69 | LTA4H (0.43) | LTA4HTSHRCA1CA2CA4 | |
| SCHEMBL31538469 | 0.69 | LTA4H (0.43) | LTA4HTSHRCA1CA2CA4 | |
| SCHEMBL188076 | 0.69 | LTA4H (0.43) | LTA4HTSHRCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937372-B1 | A METHOD OF MELT POLYMERIZING POLYCARBONATE AND POLYCARBONATES DERIVED THEREFROM | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-04-22 | — | — | EP | claimed |
| EP-2937371-A1 | A METHOD OF MELT POLYMERIZING POLYCARBONATE AND POLYCARBONATES DERIVED THEREFROM | SABIC Global Technologies B.V. (NL) | 2015-10-28 | — | — | EP | claimed |
| EP-2937372-A1 | A METHOD OF MELT POLYMERIZING POLYCARBONATE AND POLYCARBONATES DERIVED THEREFROM | SABIC Global Technologies B.V. (NL) | 2015-10-28 | — | — | EP | claimed |
| EP-3445748-B1 | METHODS OF MANUFACTURE OF 2-ARYL-3,3-BIS(4-HYDROXYARYL) PHTHALIMIDINES AND POLYMERS DERIVED THEREFROM | SHPP GLOBAL TECH BV (NL) | 2022-06-15 | — | — | EP | disclosed |
| EP-3129423-B1 | A SYSTEM AND PROCESS FOR PRODUCING VARIOUS MOLECULAR WEIGHT MELT POLYCARBONATES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2022-05-25 | — | — | EP | disclosed |
| US-11078212-B2 | 2-hydrocarbyl-3-(dihydroxyfluoresceinyl)phthalimidine monomers, methods of manufacture, and copolymers derived therefrom | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2021-08-03 | — | — | US | disclosed |
| EP-3262098-B1 | CONTROL OF ORGANIC IMPURITIES IN POLYCARBONATE SYNTHESIS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2021-06-16 | — | — | EP | disclosed |
| EP-3063202-B1 | MELT POLYMERIZATION POLYCARBONATE QUENCHING | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-12-02 | — | — | EP | disclosed |
| US-10662154-B2 | Methods of manufacture of 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidines, and polymers derived therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-05-26 | — | — | US | disclosed |
| EP-2937372-B1 | A METHOD OF MELT POLYMERIZING POLYCARBONATE AND POLYCARBONATES DERIVED THEREFROM | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-04-22 | — | — | EP | disclosed |
| CN-110746341-A | Method for purifying 2-aryl-3, 3-bis (4-hydroxyaryl) phthalimidines and polymers derived therefrom | 沙特基础工业全球技术有限公司 | 2020-02-04 | — | — | CN | disclosed |
| US-5670605-A | MELT COPOLYMERIZATION DIHYDROXYAROMATIC COMPOUNDS TO FORM POLYMERS | GENERAL ELECTRIC COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-5646233-A | HAVING OUTSTANDING HARDNESS | GENERAL ELECTRIC COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5606008-A | MELT CONDENSATION POLYMERIZATION OF AROMATIC DIHYDROXY COMPOUND AND ESTER IN THE PRESENCE OF ALIPHATIC AMINE AND ALKALI OR ALKALINE EARTH METAL COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0736574-A2 | Thermoplastic resin composition comprising carbonate and acrylic resin | GENERAL ELECTRIC COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0736561-A2 | Dihydroxy compound mixtures and polymers thereof | GENERAL ELECTRIC COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0719812-A2 | Copolycarbonate | GENERAL ELECTRIC COMPANY (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0719813-A2 | Copolycarbonate | GENERAL ELECTRIC COMPANY (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0694572-A2 | A method for manufacturing polycarbonate | GENERAL ELECTRIC COMPANY (US) | 1996-01-31 | — | — | EP | disclosed |
| EP-0694582-A2 | A glass-fiber-reinforced polycarbonate resin composition | GENERAL ELECTRIC COMPANY (US) | 1996-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078212-B2 | 2-hydrocarbyl-3-(dihydroxyfluoresceinyl)phthalimidine monomers, methods of manufacture, and copolymers derived therefrom | DPYD, DHFR, P4HTM | CA1 2834/4885CA2 1551/4885CA4 1225/4885 |
| US-10662154-B2 | Methods of manufacture of 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidines, and polymers derived therefrom | PBRM1, PAH, PHF2 | CA1 3272/4885CA2 660/4885CA4 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.