SCHEMBL144802

SCHEMBL144802

C[C@@H](C(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Na+]

nearest known ligand 0.42

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 1/20 0.42
CA1 known ✓ P00915 4/20 0.39
CA4 known ✓ P22748 3/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
NFKB1 P19838 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
FFAR3 O14843 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
CASP1 P29466 1/20 0.32
BBOX1 O75936 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15967881 1.00 CA2 (0.42) CA2CA1CA4KDM4EMAPT
Water SCHEMBL21404877 0.98 CA2 (0.41) CA2CA1CA4KDM4EMAPT
SCHEMBL1279950 0.95 CA2 (0.37) CA2CA1CA4KDM4EMAPT
SCHEMBL3064458 0.95 CA2 (0.37) CA2CA1CA4KDM4EMAPT
SCHEMBL5688204 0.95 CA2 (0.37) CA2CA1CA4KDM4EMAPT
SCHEMBL18045061 0.95 CA2 (0.37) CA2CA1CA4KDM4EMAPT
SCHEMBL3061228 0.95 CA2 (0.37) CA2CA1CA4KDM4EMAPT
Potassium Ion SCHEMBL15052919 0.95 CA2 (0.37) CA2CA1CA4KDM4EMAPT
SCHEMBL18858710 0.93 CA2 (0.36) CA2CA1CA4KDM4EMAPT
SCHEMBL4650619 0.92 CA2 (0.37) CA2CA1CA4KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 845 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119632915-A Quick and long-acting gynecological antibacterial gel and preparation method thereof 湖南现代寒湿干预研究院有限公司 2025-03-18 CN claimed
CN-118419932-B Recycling process of silicon carbide single crystal wire cutting waste mortar 山东大学 2025-02-07 CN claimed
CN-118419932-A Recycling process of silicon carbide single crystal wire cutting waste mortar 山东大学 2024-08-02 CN claimed
CN-117904642-A Aluminum alloy cleaning agent and preparation method thereof 长沙艾森设备维护技术有限公司 2024-04-19 CN claimed
CN-117858620-A Antimicrobial combinations 西姆莱斯有限公司 2024-04-09 CN claimed
US-20230364584-A1 PROCESS FOR PRODUCING SUPERABSORBENT POLYMER PARTICLES BASF SE (DE) 2023-11-16 US claimed
CN-116948751-A Detergent for removing radioactive pollutants and application thereof 中国日用化学研究院有限公司 2023-10-27 CN claimed
CN-116710590-A System for manufacturing composite copper component 纳美仕有限公司 2023-09-05 CN claimed
EP-4222239-A1 MULTIPURPOSE ALKALINE COMPOSITIONS AND METHODS OF USE Ecolab USA Inc. (US) 2023-08-09 EP claimed
EP-4214252-A1 PROCESS FOR PRODUCING SUPERABSORBENT POLYMER PARTICLES BASF SE (DE) 2023-07-26 EP claimed
EP-1454638-B1 Concentrated disinfecting composition based on quaternary ammonium compounds and their use for chemical-thermal care for instruments BODE CHEMIE GMBH (DE) 2010-12-22 EP claimed
US-20100093597-A1 ULTRA-CONCENTRATED SOLID DEGREASER COMPOSITION ECOLAB INC. (US) 2010-04-15 US claimed
US-20100093596-A1 ULTRA-CONCENTRATED LIQUID DEGREASER COMPOSITION ECOLAB INC. (US) 2010-04-15 US claimed
US-7691283-B2 Surfactant-based composition Furukawa Techno Materical Co., Ltd. (JP) 2010-04-06 US claimed
WO-2009125336-A2 ULTRA-CONCENTRATED SOLID DEGREASER COMPOSITION ECOLAB INC. (US) 2009-10-15 WO claimed
WO-2009125335-A2 ULTRA-CONCENTRATED LIQUID DEGREASER COMPOSITION ECOLAB INC. (US) 2009-10-15 WO claimed
US-20070213248-A1 Surfactant-based composition FURUKAWA TECHNO MATERIAL CO., LTD. (JP) 2007-09-13 US claimed
EP-1797926-A1 SURFACTANT COMPOSITION Furukawa Techno Material Co., Ltd (JP) 2007-06-20 EP claimed
US-20070015840-A1 Use of an alkyl ether of hydroxystilbene for the treatment of dry skin L'OREAL (FR) 2007-01-18 US claimed
US-20030161853-A1 Methylglycinediacetic acid and deribatives thereof useful as exfoliating agents L'OREAL (FR) 2003-08-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030161853-A1 Methylglycinediacetic acid and deribatives thereof useful as exfoliating agents DERL1, DDC, IDUA CA2 1453/4885CA1 2669/4885CA4 1553/4885
US-20070015840-A1 Use of an alkyl ether of hydroxystilbene for the treatment of dry skin CYP8B1, HSD17B11, HSD17B1 CA2 2569/4885CA1 1502/4885CA4 2528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.