Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL838892 | 0.82 | IDO1 (0.52) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL5417376 | 0.82 | IDO1 (0.38) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL5206144 | 0.81 | IDO1 (0.55) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL3238101 | 0.80 | IDO1 (0.41) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL150130 | 0.80 | IDO1 (0.46) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL3647884 | 0.80 | IDO1 (0.59) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL17329111 | 0.80 | IDO1 (0.59) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL18305266 | 0.79 | IDO1 (0.40) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL7504635 | 0.79 | IDO1 (0.48) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL29129467 | 0.79 | P2RX7 (0.44) | IDO1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | claimed |
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | claimed |
| EP-3169674-B1 | ARYL-TRIAZOLYL-PYRIDINES AS PESTICIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-01-20 | — | — | EP | claimed |
| US-10299478-B2 | Pyrazolyltriazolylpyridines as pesticides | BAYER ANIMAL HEALTH GMBH (DE) | 2019-05-28 | — | — | US | claimed |
| EP-3157913-B1 | PYRAZOLYL TRIAZOLYL PYRIDINES AS PESTICIDE | BAYER ANIMAL HEALTH GMBH (DE) | 2019-04-17 | — | — | EP | claimed |
| US-10208015-B2 | Aryl-triazolyl pyridines as pest control agents | BAYER ANIMAL HEALTH GMBH (DE) | 2019-02-19 | — | — | US | claimed |
| WO-2019025153-A1 | USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | claimed |
| US-10065926-B2 | Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-04 | — | — | US | claimed |
| US-20180084782-A1 | METHOD OF CONTROL OF STINKBUGS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-29 | — | — | US | claimed |
| EP-3051946-B1 | USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2017-11-29 | — | — | EP | claimed |
| WO-2004022542-A2 | SUBSTITUTED 1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | Grünenthal GmbH (DE) | 2004-03-18 | — | — | WO | claimed |
| US-6699855-B2 | PYRROLOPYRAZINONES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2004-03-02 | — | — | US | claimed |
| EP-1181279-A4 | DIKETODIAZACYCLIC COMPOUNDS, DIAZACYCLIC COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | TORREY PINES INST (US) | 2002-09-25 | — | — | EP | claimed |
| US-20020123468-A1 | Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-09-05 | — | — | US | claimed |
| US-20020065248-A1 | Inhibitors of hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-05-30 | — | — | US | claimed |
| EP-1181279-A1 | DIKETODIAZACYCLIC COMPOUNDS, DIAZACYCLIC COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2002-02-27 | — | — | EP | claimed |
| WO-2000069830-A1 | DIKETODIAZACYCLIC COMPOUNDS, DIAZACYCLIC COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2000-11-23 | — | — | WO | claimed |
| EP-0550113-B1 | Triazolopyrimidine derivatives with fungicidal activity | SHELL INT RESEARCH (NL) | 1997-10-15 | — | — | EP | claimed |
| US-5593996-A | FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1997-01-14 | — | — | US | claimed |
| EP-0550113-A2 | Triazolopyrimidine derivatives with fungicidal activity | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-07-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10065926-B2 | Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants | SQOR, DHPS, QDPR | IDO1 610/4885ALDH1A1 652/4885KDM4E 3040/4885 |
| US-10299478-B2 | Pyrazolyltriazolylpyridines as pesticides | PRDX4, PRDX1, ATL3 | IDO1 112/4885ALDH1A1 1058/4885KDM4E 1853/4885 |
| US-20020065248-A1 | Inhibitors of hepatitis C virus NS3 protease | TMPRSS15, CTRC, CPN1 | IDO1 1672/4885ALDH1A1 1353/4885KDM4E 2706/4885 |
| US-20180084782-A1 | METHOD OF CONTROL OF STINKBUGS | BROX, TUBB4B, TUBB4A | IDO1 3043/4885ALDH1A1 929/4885KDM4E 1776/4885 |
| US-10208015-B2 | Aryl-triazolyl pyridines as pest control agents | PTMS, TYR, PDXK | IDO1 8/4885ALDH1A1 2031/4885KDM4E 394/4885 |
| US-20020123468-A1 | Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease | CES1, CYP51A1, SPINT2 | IDO1 525/4885ALDH1A1 697/4885KDM4E 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.