Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682134 | 1.00 | FAAH (0.40) | FAAHCA12CA1CA9CYP2D6 | |
| SCHEMBL1604291 | 1.00 | FAAH (0.40) | FAAHCA12CA1CA9CYP2D6 | |
| SCHEMBL14764653 | 0.97 | CA12 (0.40) | FAAHCA12CA1CA9CYP2D6 | |
| SCHEMBL14764654 | 0.97 | CA12 (0.40) | FAAHCA12CA1CA9CYP2D6 | |
| SCHEMBL15912664 | 0.97 | CA12 (0.40) | FAAHCA12CA1CA9CYP2D6 | |
| SCHEMBL13491291 | 0.91 | ADORA3 (0.43) | FAAHCA12CA1CA9CYP2D6 | |
| SCHEMBL30517275 | 0.91 | G6PD (0.44) | CA12CA1CA9CYP2D6KEAP1 | |
| SCHEMBL30821470 | 0.90 | ALDH1A1 (0.40) | FAAHCA12CA1CA9CYP2D6 | |
| SCHEMBL10731427 | 0.89 | ALDH1A1 (0.43) | FAAHALDH1A1FFAR1MAPTCYP19A1 | |
| SCHEMBL7268342 | 0.88 | CYP24A1 (0.40) | CA12CA1CA9CYP2D6KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663444-B2 | Heteroatom containing substituted fatty acids | COMPLEXA, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20170113999-A9 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2017-04-27 | — | — | US | disclosed |
| US-20140256814-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| EP-2483233-A2 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | Miller, Raymond A. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041639-A2 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | MILLER RAYMOND A (US) | 2011-04-07 | — | — | WO | disclosed |
| US-20110082206-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO | 2005-10-06 | — | — | US | disclosed |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-6924309-B2 | Anti-inflammatory nitro and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2005-08-02 | — | — | US | disclosed |
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2004-12-16 | — | — | US | disclosed |
| EP-1218333-A4 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| EP-1218000-A4 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PEPLIN BIOLIPIDS PTY LTD (AU) | 2003-05-15 | — | — | US | disclosed |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2003-04-24 | — | — | US | disclosed |
| EP-1218000-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| EP-1218333-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021575-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001021172-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | FAAH 870/4885CA12 3952/4885CA1 2146/4885 |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | FAAH 992/4885CA12 3632/4885CA1 1975/4885 |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | PTGES, PTGES2, ALOX5 | FAAH 286/4885CA12 4382/4885CA1 3519/4885 |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | FAAH 1067/4885CA12 4132/4885CA1 2330/4885 |
| US-20170113999-A9 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | FAAH 53/4885CA12 3543/4885CA1 2820/4885 |
| US-20140256814-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | FAAH 53/4885CA12 3543/4885CA1 2820/4885 |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | PTGES, PTGES2, ALOX5 | FAAH 286/4885CA12 4382/4885CA1 3519/4885 |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PTGES2, PTGES, PTGS2 | FAAH 295/4885CA12 4303/4885CA1 3708/4885 |
| US-20110082206-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | FAAH 53/4885CA12 3543/4885CA1 2820/4885 |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | PTGES, PTGES2, ALOX5 | FAAH 286/4885CA12 4382/4885CA1 3519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.