Cargutocin

Cargutocin

SCHEMBL1643445

CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CCCCC[C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OXTR P30559 16/20 0.75
▸ AVPR2 P30518 13/20 0.75
▸ AVPR1A P37288 11/20 0.75
▸ AVPR1B P47901 12/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cargutocin SCHEMBL1649343 1.00 OXTR (0.75) OXTRAVPR2AVPR1AAVPR1B
Cargutocin SCHEMBL14060161 1.00 OXTR (0.75) OXTRAVPR2AVPR1AAVPR1B
Cargutocin SCHEMBL29464048 1.00 OXTR (0.75) OXTRAVPR2AVPR1AAVPR1B
SCHEMBL19003799 0.92 OXTR (0.69) OXTRAVPR2AVPR1AAVPR1B
SCHEMBL20459016 0.92 OXTR (0.69) OXTRAVPR2AVPR1AAVPR1B
SCHEMBL17150586 0.92 OXTR (0.69) OXTRAVPR2AVPR1AAVPR1B
SCHEMBL15511850 0.88 OXTR (0.88) OXTRAVPR2AVPR1AAVPR1B
SCHEMBL15512193 0.88 OXTR (0.80) OXTRAVPR2AVPR1AAVPR1B
SCHEMBL18656317 0.86 OXTR (0.74) OXTRAVPR2AVPR1AAVPR1B
SCHEMBL17150785 0.86 OXTR (0.62) OXTRAVPR2AVPR1AAVPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108236716-A A kind of pharmaceutical composition containing oxytocin analog and its preparation method and application 深圳翰宇药业股份有限公司 2018-07-03 — — CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 — — US claimed
CN-102580057-A Medicine composition containing ergometrine and oxytocin analogue and preparation method NANJING XIANYU TECHNOLOGY CO LTD 2012-07-18 — — CN claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 — — EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 — — WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US claimed
US-20030125528-A1 Process for preparing schiff base adducts of amines with o-hydroxy aldehydes and compositions of matter based thereon HAY BRUCE A (US) 2003-07-03 — — US claimed
CN-1305490-A Improved processing for preparing schift base adducts of amines with i(o)-hydroxy aldehydes and compositions of matter based thereon PFIZER PROD INC (US) 2001-07-25 — — CN claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 — — CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 — — EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 — — WO claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
WO-1996040084-A1 COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 — — WO disclosed
WO-1996040086-A2 COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF PHARMACEUTICALLY ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 — — WO disclosed
WO-1996024616-A1 PROCESS FOR PREPARING CALCITONIN AND L-α-AMINOSUBERIC ACID DERIVATIVES BY ENZYMATIC CONDENSATION LONZA AG (CH) 1996-08-15 — — WO disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS OXTR 467/4885AVPR2 1383/4885AVPR1A 1781/4885
US-20030125528-A1 Process for preparing schiff base adducts of amines with o-hydroxy aldehydes and compositions of matter based thereon OGDH, ALDH7A1, AOX1 OXTR 3362/4885AVPR2 1036/4885AVPR1A 1970/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 OXTR 77/4885AVPR2 906/4885AVPR1A 899/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 OXTR 1829/4885AVPR2 3683/4885AVPR1A 3992/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT OXTR 735/4885AVPR2 2697/4885AVPR1A 2696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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