SCHEMBL16451684

SCHEMBL16451684

Cc1nc(-c2ccccn2)nc(-c2ccccn2)n1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.78
TDP1 Q9NUW8 3/20 0.78
L3MBTL1 Q9Y468 6/20 0.59
ALOX15 P16050 4/20 0.59
TP53 P04637 4/20 0.58
METAP1 P53582 3/20 0.54
LMNA P02545 3/20 0.54
CCR1 P32246 2/20 0.54
CCR5 P51681 2/20 0.54
CCR8 P51685 2/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
SMN1; SMN2 Q16637 4/20 0.52
HTT P42858 3/20 0.52
ALPL P05186 2/20 0.52
HSP90AA1 P07900 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10550468 0.96 KDM4E (0.71) KDM4ETDP1L3MBTL1ALOX15TP53
SCHEMBL9565620 0.91 L3MBTL1 (0.68) KDM4ETDP1L3MBTL1ALOX15TP53
SCHEMBL29354466 0.89 KDM4E (1.00) KDM4ETDP1L3MBTL1ALOX15TP53
SCHEMBL322756 0.89 KDM4E (1.00) KDM4ETDP1L3MBTL1ALOX15TP53
SCHEMBL18544891 0.88 KDM4E (0.61) KDM4ETDP1L3MBTL1ALOX15TP53
SCHEMBL15131533 0.87 KDM4E (0.59) KDM4ETDP1L3MBTL1ALOX15TP53
SCHEMBL1704624 0.87 KDM4E (0.76) KDM4ETDP1L3MBTL1ALOX15TP53
SCHEMBL18482808 0.86 KDM4E (0.58) KDM4ETDP1L3MBTL1ALOX15TP53
SCHEMBL11213260 0.86 KDM4E (0.95) KDM4ETDP1L3MBTL1ALOX15TP53
SCHEMBL32681187 0.86 KDM4E (0.95) KDM4ETDP1L3MBTL1ALOX15TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718606-B2 Polycyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2023-08-08 US disclosed
US-11569453-B2 Polycyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2023-01-31 US disclosed
US-11031560-B2 Compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2021-06-08 US disclosed
US-10957857-B2 Multicyclic compound and organic light emitting device including the same LG CHEM LTD. (KR) 2021-03-23 US disclosed
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same LG CHEM, LTD. 2021-02-02 US disclosed
US-20210020848-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2021-01-21 US disclosed
US-10738034-B2 Spiro compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2020-08-11 US disclosed
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-08-04 US disclosed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
EP-3378864-B1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-04-22 EP disclosed
US-20170040547-A1 SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2017-02-09 US disclosed
US-20170040548-A1 DIPHENYLIMIDAZOLE-FUSED, SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2017-02-09 US disclosed
US-9559312-B1 Imidazole compound, material for electronic device, electroluminescent device, and electronic device thereof E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2017-01-31 US disclosed
US-9559312-B1 Imidazole compound, material for electronic device, electroluminescent device, and electronic device thereof E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2017-01-31 US disclosed
US-20160020397-A1 BORON COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-01-21 US disclosed
US-20160020397-A1 BORON COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-01-21 US disclosed
US-20150218191-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-08-06 US disclosed
US-20150218191-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-08-06 US disclosed
US-20150041785-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-02-12 US disclosed
US-20150041785-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738034-B2 Spiro compound and organic light-emitting device comprising same CRY1, NR2E3, ERG KDM4E 3633/4885TDP1 4309/4885L3MBTL1 2838/4885
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same NR2E3, ALDH1A2, CRY1 KDM4E 2977/4885TDP1 4618/4885L3MBTL1 2416/4885
US-20160020397-A1 BORON COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT EBPL, CDYL, L3MBTL3 KDM4E 567/4885TDP1 3088/4885L3MBTL1 10/4885
US-11031560-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 KDM4E 847/4885TDP1 2782/4885L3MBTL1 3030/4885
US-10957857-B2 Multicyclic compound and organic light emitting device including the same CRY1, CYP1A1, TMEM109 KDM4E 1786/4885TDP1 718/4885L3MBTL1 346/4885
US-20170040547-A1 SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SLCO2B1, SLCO4C1, SLCO1B1 KDM4E 4847/4885TDP1 2641/4885L3MBTL1 3375/4885
US-20150218191-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT EBPL, ELOC, EML4 KDM4E 1194/4885TDP1 3505/4885L3MBTL1 117/4885
US-11718606-B2 Polycyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 KDM4E 3435/4885TDP1 3131/4885L3MBTL1 3355/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 KDM4E 1258/4885TDP1 3519/4885L3MBTL1 349/4885
US-20210020848-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME PPOX, NFE2L2, OGFOD1 KDM4E 2225/4885TDP1 3440/4885L3MBTL1 1574/4885
US-20170040548-A1 DIPHENYLIMIDAZOLE-FUSED, SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SLCO4C1, SLCO2B1, SLCO1B1 KDM4E 4755/4885TDP1 3101/4885L3MBTL1 2745/4885
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same NR2E3, CRY1, CRY2 KDM4E 3335/4885TDP1 4416/4885L3MBTL1 2738/4885
US-11569453-B2 Polycyclic compound and organic light emitting element comprising same PPOX, NFE2L2, OGFOD1 KDM4E 2225/4885TDP1 3440/4885L3MBTL1 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.