Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.62 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.62 |
| ▸ | FABP2 | P12104 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611911 | 0.88 | TTR (0.67) | TTRMEN1KMT2AFTOAKR1C3 | |
| SCHEMBL10385663 | 0.86 | MEN1 (0.72) | TTRMEN1KMT2AFTOAKR1C3 | |
| SCHEMBL14580629 | 0.86 | TAS2R14 (0.70) | TTRMEN1KMT2AFTOAKR1C3 | |
| SCHEMBL1905352 | 0.82 | MAPK14 (0.83) | TTRMEN1KMT2AFTOAKR1C3 | |
| SCHEMBL2625434 | 0.82 | TAS2R14 (0.65) | TTRMEN1KMT2AAKR1C3PTGS2 | |
| SCHEMBL17424332 | 0.82 | TAS2R14 (0.61) | TTRMEN1KMT2AFTOAKR1C3 | |
| SCHEMBL13285184 | 0.82 | MPO (0.54) | MEN1KMT2AFTOAKR1C3AKR1C2 | |
| SCHEMBL9312496 | 0.81 | TTR (0.73) | TTRMEN1KMT2AFTOAKR1C3 | |
| SCHEMBL11106279 | 0.81 | AKR1C3 (0.64) | TTRMEN1KMT2AFTOAKR1C3 | |
| SCHEMBL1906857 | 0.80 | MAPK14 (0.64) | TTRMEN1KMT2AFTOAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250017846-A1 | TOPICAL ANALGESICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-01-16 | — | — | US | claimed |
| US-20210046106-A1 | METHODS OF TREATING CANCER WITH ANDROGEN DEPRIVATION THERAPY IN COMBINATION WITH AN INHIBITOR OF THE SP1 TRANSCRIPTION FACTOR | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-02-18 | — | — | US | claimed |
| US-20260102359-A1 | COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION | ERESINA LLC (US) | 2026-04-16 | — | — | US | disclosed |
| US-12564596-B2 | Agents and methods for modulating pathogen activity | GRIFFITH UNIVERSITY (AU) | 2026-03-03 | — | — | US | disclosed |
| US-12545750-B2 | Method for the diimide hydrogenation of emulsified unsaturated polymers | PARKER DANE K (US) | 2026-02-10 | — | — | US | disclosed |
| EP-4518682-A1 | USE OF NON-THERAPEUTIC ANTI-INFLAMMATORY MOLECULES IN PIGS | Vetoquinol SA (FR) | 2025-03-12 | — | — | EP | disclosed |
| US-20250017846-A1 | TOPICAL ANALGESICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-01-16 | — | — | US | disclosed |
| CN-118986994-A | Agents and methods for modulating pathogen activity | 格里菲斯大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-113164494-B | Agents and methods for modulating pathogen activity | 格里菲斯大学 | 2024-08-27 | — | — | CN | disclosed |
| US-20240084046-A1 | METHOD FOR THE DIIMIDE HYDROGENATION OF EMULSIFIED UNSATURATED POLYMERS | ROCKHILL, ALVIN T. | 2024-03-14 | — | — | US | disclosed |
| CN-117554540-A | Method for measuring nonsteroidal anti-inflammatory drug in traditional Chinese veterinary medicine preparation | 石家庄海关技术中心 | 2024-02-13 | — | — | CN | disclosed |
| US-20130245265-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2013-09-19 | — | — | US | disclosed |
| US-20130183289-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | BIOGEN IDEC MA INC (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130150395-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | KEMPHARM, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-8461137-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20130137099-A1 | TRANSGENIC REPORTER SYSTEM THAT REVEALS EXPRESSION PROFILES AND REGULATION MECHANISMS OF ALTERNATIVE SPLICING IN MAMMALIAN ORGANISMS | KYOTO UNIVERSITY (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20120142719-A1 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | ALTER DOMUS (US) LLC | 2012-06-07 | — | — | US | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-20110002990-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2011-01-06 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564596-B2 | Agents and methods for modulating pathogen activity | C3AR1, HTR3A, CHRM3 | TTR 1527/4885MEN1 865/4885KMT2A 3186/4885 |
| US-20250017846-A1 | TOPICAL ANALGESICS | OPRK1, OPRL1, OPRM1 | TTR 770/4885MEN1 4882/4885KMT2A 2996/4885 |
| US-12545750-B2 | Method for the diimide hydrogenation of emulsified unsaturated polymers | ALOX15, SOD1, ALOX12 | TTR 3005/4885MEN1 4509/4885KMT2A 2692/4885 |
| US-20260102359-A1 | COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION | COL2A1, COLGALT1, PLOD3 | TTR 586/4885MEN1 4053/4885KMT2A 1308/4885 |
| US-20110002990-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | CYP2B6, CYP3A43, CYP2D6 | TTR 2597/4885MEN1 4302/4885KMT2A 788/4885 |
| US-20120142719-A1 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | CYP2B6, CYP3A43, CYP2D6 | TTR 2597/4885MEN1 4302/4885KMT2A 788/4885 |
| US-20130150395-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, CYP2D6 | TTR 2354/4885MEN1 3911/4885KMT2A 1565/4885 |
| US-20130245265-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | CYP2B6, CYP3A43, CYP2D6 | TTR 2597/4885MEN1 4302/4885KMT2A 788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.