Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL16611

O=P([O-])([O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 2/20 0.37
CA4 known ✓ P22748 2/20 0.37
FDPS known ✓ P14324 1/20 0.33
LMNA P02545 2/20 0.38
CA5A P35218 2/20 0.37
CA5B Q9Y2D0 2/20 0.37
SLC34A1 Q06495 1/20 0.36
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
BTN3A1 O00481 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL378579 1.00 LMNA (0.38) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL6037596 1.00 LMNA (0.38) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL14126194 1.00 LMNA (0.38) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL1354726 1.00 LMNA (0.38) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL2387459 1.00 LMNA (0.38) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL23537582 1.00 LMNA (0.38) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL22749765 0.95 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL21712339 0.95 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL23537579 0.95 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL20699882 0.95 LMNA (0.35) LMNACA1CA4CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 120326 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144278-A1 METHODS AND SYSTEMS FOR STERILIZING NATURAL PRODUCTS Material Futures Inc. (CA) 2026-05-28 US claimed
CN-122075668-A Composition and method for vancomycin oral liquid 2026-05-26 CN claimed
CN-122079554-A Solid waste matrix homogenate and preparation method thereof 2026-05-26 CN claimed
CN-122076475-A In-situ doped TiO with wide particle size range2Core-shell structure powder and preparation method and application thereof 2026-05-26 CN claimed
CN-122079098-A Preparation method of low-viscosity basic ferric phosphate slurry and product thereof 2026-05-26 CN claimed
CN-122079108-A Na with high compaction densityaFeb(PO4)cP2O7Preparation method of/C material 2026-05-26 CN claimed
CN-122075376-A An oral cavity cough liquid for preventing and treating stomatocace and refreshing breath, and its preparation method 2026-05-26 CN claimed
CN-121182470-B Composite temporary plugging agent applicable to different temperature gradients and preparation method thereof CHINA UNIVERSITY OF PETROLEUM (EAST CHINA) (CN) 2026-05-26 CN claimed
CN-122080673-A Rare earth nano coating with high bonding energy and preparation method and application thereof 2026-05-26 CN claimed
CN-119725837-B Method for recycling lithium, iron, phosphorus and graphite in waste lithium iron phosphate battery in grading manner ZHEJIANG UNIVERSITY (CN) 2026-05-26 CN claimed
US-3963634-A SODIUM PERCARBONATE, PARTICLE SIZES KAO SOAP CO., LTD. (JA) 1976-06-15 US claimed
US-3962495-A Method of making duplicates of optical or sound recordings RCA CORPORATION (US) 1976-06-08 US claimed
US-3960901-A Preparation of citraconic acid PFIZER INC. (US) 1976-06-01 US claimed
US-3960580-A OXY-BORON COMPOUNDS, EXTEND THE SETTING TIME W. R. GRACE & CO. (US) 1976-06-01 US claimed
US-3958997-A Method of shaker molding and composition therefor GREENBERG ALLEN A 1976-05-25 US claimed
US-3951839-A HYDROXY COMPOUND ANTIOXIDANT, BLEACH KAO SOAP CO., LTD. (JA) 1976-04-20 US claimed
US-3949560-A BENTONITE; PHOSPHATE, SULFATE OR SALT OF LEONARDITE DISPERSANT; POLYMER AMERICAN COLLOID COMPANY (US) 1976-04-13 US claimed
US-3939100-A Combination alkali metal pyrophosphate-alkaline earth metal pyrophosphate detergent builder THE PROCTER & GAMBLE COMPANY (US) 1976-02-17 US claimed
US-3934049-A ALKALI METAL PYROPHOSHATE AND CARBONATE, ALKALINE EARTH METAL ORTHO-PHOSPHATE, AND PREGELATINIZED STARCH OR GUMS STAUFFER CHEMICAL COMPANY (US) 1976-01-20 US claimed
US-3931396-A TIN PYROPHOSPHATE COMPLEX, RADIOACTIVITY COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1976-01-06 US claimed