Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.37 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.37 |
| ▸ | FDPS known ✓ | P14324 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL16611 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL6037596 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL14126194 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL1354726 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL2387459 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL23537582 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL22749765 | 0.95 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL21712339 | 0.95 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL23537579 | 0.95 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL20699882 | 0.95 | LMNA (0.35) | LMNACA1CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11806836-B2 | Calcium carbonate slurry | ILLUMINA, INC. (US) | 2023-11-07 | — | — | US | claimed |
| US-20230180805-A1 | Opacifying Agents | EFCO Products Inc. (US) | 2023-06-15 | — | — | US | claimed |
| US-20220089910-A1 | CALCIUM CARBONATE SLURRY | ILLUMINA, INC. | 2022-03-24 | — | — | US | claimed |
| CN-110546221-B | Calcium carbonate slurry | 伊鲁米那股份有限公司 | 2022-02-22 | — | — | CN | claimed |
| US-11214712-B2 | Calcium carbonate slurry | ILLUMINA, INC. (US) | 2022-01-04 | — | — | US | claimed |
| EP-3585846-B1 | CALCIUM CARBONATE SLURRY | ILLUMINA INC (US) | 2021-11-10 | — | — | EP | claimed |
| US-10706981-B2 | Method for decontaminating radiocontaminated grains | CORELEX SAN-EI CO., LTD. (JP) | 2020-07-07 | — | — | US | claimed |
| CN-110546221-A | Calcium carbonate slurry | ILLUMINA INC | 2019-12-06 | — | — | CN | claimed |
| US-20180330838-A1 | METHOD FOR DECONTAMINATING RADIOCONTAMINATED GRAINS | CORELEX SAN-EI CO., LTD. (JP) | 2018-11-15 | — | — | US | claimed |
| EP-3373306-A1 | METHOD FOR DECONTAMINATING GRANULAR MATERIAL CONTAMINATED BY RADIOACTIVE MATERIAL | Corelex San-Ei Co., Ltd. (JP) | 2018-09-12 | — | — | EP | claimed |
| US-5427707-A | Automatic dishwashing gel | COLGATE PALMOLIVE CO. (US) | 1995-06-27 | — | — | US | claimed |
| US-5296100-A | Precomplexing of metal impurities | ATOCHEM (FR) | 1994-03-22 | — | — | US | claimed |
| US-5143581-A | METHOD OF PEROXIDE BLEACHING OF PULP PRETREATED WITH A SEQUESTERING AGENT THEN WITH A SULPHITE AND REDUCING AGENT | ATOCHEM (FR) | 1992-09-01 | — | — | US | claimed |
| US-4812206-A | Process for bleaching lignocellulosic matter | ATOCHEM (FR) | 1989-03-14 | — | — | US | claimed |
| US-4485871-A | In-situ process for recovering hydrocarbons from a diatomite-type formation | CHEVRON RESEARCH COMPANY (US) | 1984-12-04 | — | — | US | claimed |
| US-4374153-A | Process for controlling the pinking of onions | SCM CORPORATION (US) | 1983-02-15 | — | — | US | claimed |
| US-4307125-A | Low fat butter-like spread | GAY-LEA FOODS CO-OPERATIVE LIMITED (CA) | 1981-12-22 | — | — | US | claimed |
| US-4276204-A | Composition of a conductive ceramic glaze and improved method of forming same | GENERAL PORCELAIN MFG. CO. (US) | 1981-06-30 | — | — | US | claimed |
| US-4183830-A | FELDSPAR, FLINT, CALCIUM CARBONATE, BALL CLAY, KAOLIN, BARIUM CARBONATE, RED IRON OXIDE | GENERAL PORCELAIN MFG. CO. (US) | 1980-01-15 | — | — | US | claimed |
| US-4058472-A | ALKALI METAL OR AMMONIUM SULFONATED CATECHOL | TEXACO INC. (US) | 1977-11-15 | — | — | US | claimed |