Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.37 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.37 |
| ▸ | FDPS known ✓ | P14324 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL16611 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL378579 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL6037596 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL14126194 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL1354726 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL23537582 | 1.00 | LMNA (0.38) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL22749765 | 0.95 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL21712339 | 0.95 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL23537579 | 0.95 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL20699882 | 0.95 | LMNA (0.35) | LMNACA1CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2017228-B1 | PROCESS FOR PRODUCING FRESHWATER | TORAY INDUSTRIES (JP) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012113724-A2 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULFIDE/THIOL FUNCTION, A SPARINGLY OR NON-ETHOXYLATED FATTY ALCOHOL, A CATIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'OREAL (FR) | 2012-08-30 | — | — | WO | disclosed |
| US-20110226695-A1 | METHOD FOR PRODUCING FRESH WATER | TORAY INDUSTRIES, INC. (JP) | 2011-09-22 | — | — | US | disclosed |
| EP-2017228-A1 | PROCESS FOR PRODUCING FRESHWATER | TORAY INDUSTRIES, INC. (JP) | 2009-01-21 | — | — | EP | disclosed |
| WO-2003011058-A1 | FORMULATIONS OF COMPOUNDS DERIVED FROM NATURAL SOURCES AND THEIR USE WITH IRRADIATION FOR FOOD PRESERVATION | INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) | 2003-02-13 | — | — | WO | disclosed |
| EP-1235543-A1 | TARTAR CONTROL DENTURE ADHESIVE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001041712-A1 | TARTAR CONTROL DENTURE ADHESIVE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |