Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fluorescein. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS known ✓ | P04818 | 1/20 | 0.45 |
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.45 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 2/20 | 0.72 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.72 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorescein SCHEMBL11240448 | 0.85 | FTO (0.89) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL8345842 | 0.85 | FTO (0.94) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL27654958 | 0.85 | FTO (0.94) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL28633518 | 0.85 | FTO (0.94) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL29371199 | 0.85 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL16533 | 0.85 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL30272223 | 0.85 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL29388667 | 0.85 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL3645090 | 0.85 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL7763903 | 0.84 | MAPT (0.67) | FTOMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100268169-A1 | AUTOINJECTOR WITH DESHIELDER COMPRISING TAMPER EVIDENCE MEANS | BECTON DICKINSON FRANCE S.A.S. (FR) | 2010-10-21 | — | — | US | claimed |
| US-7754488-B2 | Rapid analysis of functional fluids | THE LUBRIZOL CORPORATION (US) | 2010-07-13 | — | — | US | claimed |
| EP-2126551-A1 | ANALYSIS OF FUNCTIONAL FLUIDS | THE LUBRIZOL CORPORATION (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008106337-A1 | ANALYSIS OF FUNCTIONAL FLUIDS | THE LUBRIZOL CORPORATION (US) | 2008-09-04 | — | — | WO | claimed |
| US-20080206874-A1 | Analysis of Functional Fluids | THE LUBRIZOL CORPORATION (US) | 2008-08-28 | — | — | US | claimed |
| EP-1875227-A1 | RAPID ANALYSIS OF FUNCTIONAL FLUIDS | The Lubrizol Corporation (US) | 2008-01-09 | — | — | EP | claimed |
| WO-2006112827-A1 | RAPID ANALYSIS OF FUNCTIONAL FLUIDS | THE LUBRIZOL CORPORATION (US) | 2006-10-26 | — | — | WO | claimed |
| US-20050227369-A1 | Rapid analysis of functional fluids | THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO (US) | 2005-10-13 | — | — | US | claimed |
| EP-2057275-B1 | ARRAY FOR RAPID DETECTION OF A MICROORGANISM | KIMBERLY CLARK CO (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2056890-B1 | METHOD FOR DETECTING CANDIDA ON SKIN | KIMBERLY CLARK CO (US) | 2015-11-18 | — | — | EP | disclosed |
| US-8617874-B2 | Array for rapid detection of a microorganism | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| US-8361742-B2 | Method for detecting Candida on skin | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| EP-2195655-B1 | RAPID ASSESSMENT OF UPPER RESPIRATORY CONDITIONS | KIMBERLY CLARK CO (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2303588-A2 | TEMPORARY TATTOO DECALS FOR DETECTING THE PRESENCE OF AN ANALYTE | Kimberly-Clark Worldwide, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2008026105-A2 | METHOD FOR DETECTING CANDIDA ON SKIN | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2008026104-A2 | ARRAY FOR RAPID DETECTION OF A MICROORGANISM | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2008-03-06 | — | — | WO | disclosed |
| US-20080057533-A1 | Array for rapid detection of a microorganism | KIMBERLY-CLARK WORLDWIDE, INC. | 2008-03-06 | — | — | US | disclosed |
| EP-1875227-A1 | RAPID ANALYSIS OF FUNCTIONAL FLUIDS | The Lubrizol Corporation (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006112827-A1 | RAPID ANALYSIS OF FUNCTIONAL FLUIDS | THE LUBRIZOL CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |
| US-20050227369-A1 | Rapid analysis of functional fluids | THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO (US) | 2005-10-13 | — | — | US | disclosed |