Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441359 | 0.88 | MEN1 (0.35) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL29994889 | 0.87 | CA1 (0.39) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL28513985 | 0.86 | TP53 (0.38) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL15420991 | 0.84 | MEN1 (0.32) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL28534407 | 0.84 | TSHR (0.41) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL6689822 | 0.82 | TP53 (0.35) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL2282335 | 0.82 | — | — | |
| SCHEMBL5149657 | 0.80 | — | — | |
| SCHEMBL9004902 | 0.80 | ENPEP (0.48) | ALDH1A1TSHRTP53ENPEP | |
| SCHEMBL28098009 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112023726-B | Low-energy-consumption high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-112023726-A | Low-energy-consumption high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-12-04 | — | — | CN | claimed |
| CN-112023726-B | Low-energy-consumption high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114728255-A | Microspheres containing ionic groups and method for producing same | 株式会社德山 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021117837-A1 | IONIC-GROUP-CONTAINING MICROBALLOON AND PRODUCTION METHOD THEREFOR | 株式会社トクヤマ | 2021-06-17 | — | — | WO | disclosed |
| CN-112023726-A | Low-energy-consumption high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-12-04 | — | — | CN | disclosed |
| EP-2576657-B1 | METHODS FOR PRODUCING CROSSLINKABLE SILYL GROUP-CONTAINING POLYOXYALKYLENE POLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-01-18 | — | — | EP | disclosed |
| US-8916669-B2 | Methods for producing crosslinkable silyl group-containing polyoxyalkylene polymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-12-23 | — | — | US | disclosed |
| EP-2576657-A2 | METHODS FOR PRODUCING CROSSLINKABLE SILYL GROUP-CONTAINING POLYOXYALKYLENE POLYMERS | Dow Global Technologies LLC (US) | 2013-04-10 | — | — | EP | disclosed |
| US-20130060000-A1 | METHODS FOR PRODUCING CROSSLINKABLE SILYL GROUP-CONTAINING POLYOXYALKYLENE POLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-03-07 | — | — | US | disclosed |
| WO-2011150161-A2 | METHODS FOR PRODUCING CROSSLINKABLE SILYL GROUP-CONTAINING POLYOXYALKYLENE POLYMERS. | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-01 | — | — | WO | disclosed |
| US-7094833-B2 | Block copolymer | KANEKA CORPORATION | 2006-08-22 | — | — | US | disclosed |
| US-6992138-B2 | Polyurethane polymer | KANEKA CORPORATION (JP) | 2006-01-31 | — | — | US | disclosed |
| US-20040236020-A1 | Block copolymer | KANEKA CORPORATION (JP) | 2004-11-25 | — | — | US | disclosed |
| US-20040171765-A1 | Polyurethane polymer | KANEKA CORPORATION (JP) | 2004-09-02 | — | — | US | disclosed |
| US-20040106732-A1 | Thermoplastic resin composition and elastomer composition | KANEKA CORPORATION (JP) | 2004-06-03 | — | — | US | disclosed |
| EP-1411070-A1 | BLOCK COPOLYMER | KANEKA CORPORATION (JP) | 2004-04-21 | — | — | EP | disclosed |
| US-6503995-B2 | Hydrosilation | KANEKA CORPORATION (JP) | 2003-01-07 | — | — | US | disclosed |
| US-20020013427-A1 | Method of producing crosslinkable silyl group-containing polyoxyalkylene polymers | KANEKA CORPORATION (JP) | 2002-01-31 | — | — | US | disclosed |
| EP-1146062-A1 | Method of producing crosslinkable silyl group-containing polyoxyalkylene polymers | Kaneka Corporation (JP) | 2001-10-17 | — | — | EP | disclosed |