Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441359 | 0.87 | MEN1 (0.35) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL28513985 | 0.85 | TP53 (0.38) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL1695398 | 0.82 | MEN1 (0.39) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL9004902 | 0.79 | ENPEP (0.48) | TP53ALDH1A1TSHR | |
| SCHEMBL5149657 | 0.79 | — | — | |
| SCHEMBL28542127 | 0.77 | FUT7 (0.39) | TP53 | |
| SCHEMBL621335 | 0.77 | — | — | |
| SCHEMBL9403050 | 0.76 | TP53 (0.35) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL891108 | 0.76 | GPR84 (0.47) | TP53TSHR | |
| SCHEMBL2383941 | 0.76 | GPR84 (0.47) | TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393613-A | Easily-dispersible self-extinction waterborne polyurethane curing agent and preparation method thereof | 广东巴德富新材料有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-117026682-A | Paper leather production process | 浙江一树纸业集团有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116496705-A | Adhesive film, laminate, and method for using adhesive film | DIC株式会社 | 2023-07-28 | — | — | CN | disclosed |
| US-20230235201-A1 | PSA FILM, LAMINATE, AND METHOD FOR USING PSA FILM | DIC CORPORATION (JP) | 2023-07-27 | — | — | US | disclosed |
| CN-114790293-B | Poly (siloxane-hetero thioether) dihydric alcohol, aqueous polyurethane and polyurethane elastomer and preparation method thereof | 山东大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114790293-A | Poly (siloxane-hetero thioether) dihydric alcohol, waterborne polyurethane and polyurethane elastomer and preparation method thereof | 山东大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-112661933-A | Preparation method of reactive waterborne polyurethane | 武汉弘毅共聚新材料科技有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-110295503-A | A kind of preparation method of waterborne polyurethane synthetic leather | 福建禾欣中裕新材料有限公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-105385327-A | Low-viscosity flame-retardant polyurethane metal paint | NINGGUO LONGSHI METAL PRODUCT CO LTD | 2016-03-09 | — | — | CN | disclosed |
| CN-102529257-A | Transfer printing laminated body | NIPPON SYNTHETIC CHEM IND | 2012-07-04 | — | — | CN | disclosed |
| WO-2004078826-A1 | BIODEGRADABLE ALPHATIC POLYESTER IONOMERIC RESIN AND ITS PREPARING METHOD | HANYANG HAKWON CO., LTD. (KR) | 2004-09-16 | — | — | WO | disclosed |