Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695398 | 0.86 | MEN1 (0.39) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL6689822 | 0.85 | TP53 (0.35) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL8441359 | 0.81 | MEN1 (0.35) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL28098009 | 0.78 | — | — | |
| SCHEMBL15420991 | 0.77 | MEN1 (0.32) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL28534407 | 0.77 | TSHR (0.41) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL6838775 | 0.76 | TP53 (0.39) | TP53MEN1ALDH1A1TSHRKMT2A | |
| Sulfuric Acid SCHEMBL922031 | 0.76 | THRB (0.48) | TP53THRBMEN1ALDH1A1TSHR | |
| SCHEMBL29994889 | 0.75 | CA1 (0.39) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL25231278 | 0.75 | THRB (0.38) | TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025108924-A1 | WATER-DISPERSIBLE BLOCKED ISOCYANATE PREPOLYMER SYSTEM, METHOD FOR PREPARING THE SAME, AND APPLICATION THEREOF | COVESTRO DEUTSCHLAND AG (DE) | 2025-05-30 | — | — | WO | claimed |
| CN-115819714-A | Preparation method and application of waterborne polyurethane composition | 万华化学集团股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-115109219-A | Multiple self-crosslinking type water-based hybrid resin and preparation method and application thereof | 烟台金桥优尼科新材料科技有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-114181353-A | Synthesis and application of modified waterborne polyurethane composition | 万华化学集团股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114106285-A | Multiple self-crosslinking type water-based hybrid resin and preparation method and application thereof | 烟台金桥优尼科新材料科技有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-113956430-A | Waterborne polyurethane adhesive resin and preparation method thereof | 广州市纬庆化工科技有限公司 | 2022-01-21 | — | — | CN | claimed |
| CN-112321774-A | Waterborne polyurethane/acrylate composite emulsion for single-component plastic silver paint and preparation method thereof | 湖北双键精细化工有限公司 | 2021-02-05 | — | — | CN | claimed |
| WO-2025108924-A1 | WATER-DISPERSIBLE BLOCKED ISOCYANATE PREPOLYMER SYSTEM, METHOD FOR PREPARING THE SAME, AND APPLICATION THEREOF | COVESTRO DEUTSCHLAND AG (DE) | 2025-05-30 | — | — | WO | disclosed |
| CN-112321774-B | Waterborne polyurethane/acrylate composite emulsion for single-component plastic silver paint and preparation method thereof | 湖北双键精细化工有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-115109219-A | Multiple self-crosslinking type water-based hybrid resin and preparation method and application thereof | 烟台金桥优尼科新材料科技有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114106285-A | Multiple self-crosslinking type water-based hybrid resin and preparation method and application thereof | 烟台金桥优尼科新材料科技有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-112661933-A | Preparation method of reactive waterborne polyurethane | 武汉弘毅共聚新材料科技有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-112321774-A | Waterborne polyurethane/acrylate composite emulsion for single-component plastic silver paint and preparation method thereof | 湖北双键精细化工有限公司 | 2021-02-05 | — | — | CN | disclosed |