Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695398 | 0.79 | MEN1 (0.39) | — | |
| SCHEMBL28513985 | 0.78 | TP53 (0.38) | — | |
| SCHEMBL9004853 | 0.74 | MEN1 (0.35) | — | |
| SCHEMBL10779909 | 0.74 | — | — | |
| SCHEMBL3424155 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL1280536 | 0.74 | — | — | |
| SCHEMBL28680211 | 0.74 | — | — | |
| SCHEMBL1030928 | 0.74 | MEN1 (0.35) | — | |
| SCHEMBL8441359 | 0.74 | MEN1 (0.35) | — | |
| SCHEMBL6689822 | 0.74 | TP53 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110330620-A | Plastic film water-based polyurethane ink binder and preparation method thereof | 山西省应用化学研究所(有限公司) | 2019-10-15 | — | — | CN | claimed |
| CN-110396338-B | Double-component permeable reactive waterproof coating and preparation method and application thereof | 江苏凯伦建材股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-111072905-A | Polyurethane self-skinning cushion water-based coating and polyurethane self-skinning cushion | 鹤山市鹤威科技发展有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-109575224-A | A kind of preparation method of sulfonate type photocuring aqueous polyurethane | 江西原石科技有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-105601567-B | Fluorescent dye monomer, fluorescent copolymer lotion and preparation method thereof | 江苏李文甲化工有限公司 | 2019-01-29 | — | — | CN | disclosed |
| CN-103881049-B | The preparation method of eleostearic acid monoglyceride modified aqueous polyurethane emulsion | 中南林业科技大学 | 2016-09-28 | — | — | CN | disclosed |
| CN-103881053-B | The preparation method of tung oil acid anhydride ester polyol modified aqueous polyurethane emulsion | 中南林业科技大学 | 2016-09-28 | — | — | CN | disclosed |