Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.33 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253527 | 0.78 | — | — | |
| SCHEMBL905194 | 0.78 | — | — | |
| SCHEMBL725364 | 0.78 | — | — | |
| SCHEMBL27489343 | 0.77 | ALDH1A1 (0.37) | TSHRSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL3205794 | 0.77 | — | — | |
| Water SCHEMBL23295864 | 0.77 | ALDH1A1 (0.37) | TSHRSMN1; SMN2MAPTNPC1RAB9A | |
| Methane SCHEMBL8576129 | 0.77 | ALDH1A1 (0.37) | TSHRSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL11691480 | 0.77 | — | — | |
| SCHEMBL30998824 | 0.75 | CA14 (0.42) | TSHRSMN1; SMN2MAPTKMT2ANPSR1 | |
| SCHEMBL5605327 | 0.75 | CA14 (0.42) | TSHRSMN1; SMN2MAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180049438-A1 | NITRIFICATION INHIBITOR COMPOSITIONS AND METHODS FOR PREPARING THE SAME | CORTEVA AGRISCIENCE LLC | 2018-02-22 | — | — | US | claimed |
| EP-3240768-A2 | NITRIFICATION INHIBITOR COMPOSITIONS AND METHODS FOR PREPARING THE SAME | Dow AgroSciences LLC (US) | 2017-11-08 | — | — | EP | claimed |
| WO-2016108927-A2 | NITRIFICATION INHIBITOR COMPOSITIONS AND METHODS FOR PREPARING THE SAME | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | claimed |
| CN-118360613-A | Phosphorus-free low-COD metal oil and wax removal powder and preparation method and application thereof | 广州三孚新材料科技股份有限公司 | 2024-07-19 | — | — | CN | disclosed |
| US-20180049438-A1 | NITRIFICATION INHIBITOR COMPOSITIONS AND METHODS FOR PREPARING THE SAME | CORTEVA AGRISCIENCE LLC | 2018-02-22 | — | — | US | disclosed |
| US-8357392-B2 | Dry antiseptic wipes comprising an amphoteric surfactant | KELLY ALBERT R (US) | 2013-01-22 | — | — | US | disclosed |
| US-20120055510-A1 | Antiseptic Wipes | KELLY ALBERT R (US) | 2012-03-08 | — | — | US | disclosed |
| US-20100272602-A1 | Antiseptic wipes | KELLY ALBERT R | 2010-10-28 | — | — | US | disclosed |
| US-20100136079-A1 | Antiseptic wipes | KELLY ALBERT R | 2010-06-03 | — | — | US | disclosed |
| US-7723418-B2 | Antistatic resin composition | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-20050049360-A1 | Mixture of thermoplastic resin and antistatic agents; polyamideesterether block polymers | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-0063609-A1 | COMPOSITION FOR PRODUCING INORGANIC FOAM | SHIKOKU KAKEN KOGYO KABUSHIKI KAISHA (JP) | 1982-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120055510-A1 | Antiseptic Wipes | PRKDC, KRT18, TK1 | CA2 2801/4885CA1 2617/4885TSHR 3146/4885 |
| US-20100272602-A1 | Antiseptic wipes | PRKDC, KRT18, TK1 | CA2 2801/4885CA1 2617/4885TSHR 3146/4885 |
| US-20100136079-A1 | Antiseptic wipes | POLR1C, CUTA, PRKDC | CA2 2839/4885CA1 3539/4885TSHR 3052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.