Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30472433 | 1.00 | GABRA1 (0.37) | GABRA1GABRB2POLBCTSDBACE1 | |
| SCHEMBL31749284 | 0.84 | NOTUM (0.34) | CHRNB4CHRNA3NOTUM | |
| SCHEMBL5779081 | 0.84 | NOTUM (0.34) | CHRNB4CHRNA3NOTUM | |
| SCHEMBL30697388 | 0.83 | CHRNB4 (0.39) | GABRA1GABRB2POLBCHRNB4CHRNA3 | |
| SCHEMBL27018947 | 0.83 | CHRNB4 (0.39) | GABRA1GABRB2POLBCHRNB4CHRNA3 | |
| SCHEMBL26709197 | 0.82 | VEGFA (0.35) | ALDH1A1MAPT | |
| SCHEMBL31075912 | 0.82 | NOTUM (0.33) | HIF1ACHRNB4CHRNA3NOTUMALDH1A1 | |
| SCHEMBL190968 | 0.82 | GABRA1 (0.52) | GABRA1GABRB2POLBCYP1A2CYP2D6 | |
| SCHEMBL846677 | 0.82 | GABRA1 (0.46) | GABRA1GABRB2POLBCYP1A2CYP2D6 | |
| SCHEMBL179354 | 0.82 | GABRA1 (0.46) | GABRA1GABRB2POLBCYP2C19HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648762-A2 | PPARG MODULATORS | University of Florida Research Foundation, Incorporated (US) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |
| CN-118344392-A | Light-emitting element and condensed polycyclic compound for use in the same | 三星显示有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118146242-A | Light-emitting element and polycyclic compound used for the same | 三星显示有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20240023439-A1 | LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20240023439-A1 | LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20230250082-A1 | 4-ETHYNYLPYRIDINE DERIVATIVES USEFUL AS GCN2 INHIBITORS | IP2IPO INNOVATIONS LIMITED (GB) | 2023-08-10 | — | — | US | disclosed |
| US-20230250082-A1 | 4-ETHYNYLPYRIDINE DERIVATIVES USEFUL AS GCN2 INHIBITORS | IP2IPO INNOVATIONS LIMITED (GB) | 2023-08-10 | — | — | US | disclosed |
| US-20230219981-A1 | LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-07-13 | — | — | US | disclosed |
| US-20110230498-A1 | BIARYL CARBOXAMIDES | MERCK SHARP & DOHME CORP. | 2011-09-22 | — | — | US | disclosed |
| CN-101835771-A | Aminobenzyl-substituted cyclic sulfones useful as bace inhibitors | NOVARTIS AG | 2010-09-15 | — | — | CN | disclosed |
| WO-2010100070-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100070-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-10 | — | — | WO | disclosed |
| US-20100222325-A1 | Inhibitors of Bruton's Tyrosine Kinase | BERTHEL STEVEN | 2010-09-02 | — | — | US | disclosed |
| US-20100222325-A1 | Inhibitors of Bruton's Tyrosine Kinase | BERTHEL STEVEN | 2010-09-02 | — | — | US | disclosed |
| US-20100222325-A1 | Inhibitors of Bruton's Tyrosine Kinase | BERTHEL STEVEN | 2010-09-02 | — | — | US | disclosed |
| EP-2190833-A1 | AMINOBENZYL-SUBSTITUTED CYCLIC SULFONES USEFUL AS BACE INHIBITORS | Novartis Ag (CH) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009024615-A1 | AMINOBENZYL-SUBSTITUTED CYCLIC SULFONES USEFUL AS BACE INHIBITORS | NOVARTIS AG (CH) | 2009-02-26 | — | — | WO | disclosed |
| US-20090054427-A1 | AMINOBENZYL-SUBSTITUTED CYCLIC SULFONES USEFUL AS BACE INHIBITORS | BRIARD EMMANUELLE | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250082-A1 | 4-ETHYNYLPYRIDINE DERIVATIVES USEFUL AS GCN2 INHIBITORS | EIF2AK4, GCN1, EIF5B | GABRA1 4178/4885GABRB2 3396/4885POLB 2508/4885 |
| US-20240023439-A1 | LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME | LAGE3, TMEM109, ESR1 | GABRA1 2274/4885GABRB2 2988/4885POLB 4350/4885 |
| US-20110230498-A1 | BIARYL CARBOXAMIDES | PAFAH1B3, PAFAH1B2, FAAH2 | GABRA1 636/4885GABRB2 940/4885POLB 2900/4885 |
| US-20090054427-A1 | AMINOBENZYL-SUBSTITUTED CYCLIC SULFONES USEFUL AS BACE INHIBITORS | BACE2, BACE1, APP | GABRA1 413/4885GABRB2 135/4885POLB 591/4885 |
| US-20230219981-A1 | LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME | ELP1, NFE2L2, LEF1 | GABRA1 1848/4885GABRB2 2574/4885POLB 2742/4885 |
| US-20100222325-A1 | Inhibitors of Bruton's Tyrosine Kinase | BTK, SYK, LYN | GABRA1 2265/4885GABRB2 2888/4885POLB 2572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.