Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17672767 | 0.78 | PTGS2 (0.48) | PTGS2CYP3A4TSHRHSD17B10GPR84 | |
| SCHEMBL19546176 | 0.77 | GPR84 (0.45) | PTGS2CYP3A4TSHRHSD17B10GPR84 | |
| SCHEMBL17672771 | 0.73 | ALDH1A1 (0.54) | PTGS2CYP3A4TSHRHSD17B10GPR84 | |
| SCHEMBL19166235 | 0.73 | GPR84 (0.50) | PTGS2CYP3A4TSHRGPR84MEN1 | |
| SCHEMBL1671839 | 0.71 | PTGS2 (0.55) | PTGS2CYP3A4TSHRHSD17B10GPR84 | |
| SCHEMBL692706 | 0.71 | PTGS2 (0.55) | PTGS2CYP3A4TSHRHSD17B10GPR84 | |
| SCHEMBL17672982 | 0.71 | GPR84 (0.67) | PTGS2CYP3A4TSHRGPR84MEN1 | |
| SCHEMBL24217799 | 0.70 | LIPG (0.50) | PTGS2TSHRHSD17B10ALOX5TLR8 | |
| SCHEMBL19166806 | 0.70 | KAT8 (0.54) | PTGS2CYP3A4GPR84RARB | |
| SCHEMBL17672988 | 0.70 | CA2 (0.42) | PTGS2CYP3A4TSHRGPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107106526-B | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | 普罗米蒂克医药SMT有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-106999458-B | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of diabetes | 普罗米蒂克医药SMT有限公司 | 2021-04-13 | — | — | CN | disclosed |
| US-20210085626-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | LIMINAL BIOSCIENCES LTD (GB) | 2021-03-25 | — | — | US | disclosed |
| US-20210085626-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | LIMINAL BIOSCIENCES LTD (GB) | 2021-03-25 | — | — | US | disclosed |
| EP-3203998-B1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DIABETES | LIMINAL BIOSCIENCES LTD (GB) | 2021-03-10 | — | — | EP | disclosed |
| EP-3203998-B1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DIABETES | LIMINAL BIOSCIENCES LTD (GB) | 2021-03-10 | — | — | EP | disclosed |
| US-10869849-B2 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | Liminal Biosciences Limited (GB) | 2020-12-22 | — | — | US | disclosed |
| US-10869849-B2 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | Liminal Biosciences Limited (GB) | 2020-12-22 | — | — | US | disclosed |
| US-20200078324-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | Liminal Biosciences Limited (GB) | 2020-03-12 | — | — | US | disclosed |
| US-10391073-B2 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | PROMETIC PHARMA SMT LIMITED (GB) | 2019-08-27 | — | — | US | disclosed |
| US-20170312237-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | Liminal Biosciences Limited (GB) | 2017-11-02 | — | — | US | disclosed |
| EP-3217968-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | PROMETIC PHARMA SMT LIMITED (GB) | 2017-09-20 | — | — | EP | disclosed |
| EP-3203998-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DIABETES | PROMETIC PHARMA SMT LIMITED (GB) | 2017-08-16 | — | — | EP | disclosed |
| US-20170209399-A1 | Substituted Aromatic Compounds and Pharmaceutical Compositions For The Prevention And Treatment Of Diabetes | PROMETIC PHARMA SMT LIMITED (GB) | 2017-07-27 | — | — | US | disclosed |
| US-20170209399-A1 | Substituted Aromatic Compounds and Pharmaceutical Compositions For The Prevention And Treatment Of Diabetes | PROMETIC PHARMA SMT LIMITED (GB) | 2017-07-27 | — | — | US | disclosed |
| US-20170209399-A1 | Substituted Aromatic Compounds and Pharmaceutical Compositions For The Prevention And Treatment Of Diabetes | PROMETIC PHARMA SMT LIMITED (GB) | 2017-07-27 | — | — | US | disclosed |
| WO-2016074068-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | PROMETIC BIOSCIENCES INC. (CA) | 2016-05-19 | — | — | WO | disclosed |
| WO-2016074068-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | PROMETIC BIOSCIENCES INC. (CA) | 2016-05-19 | — | — | WO | disclosed |
| WO-2016054726-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DIABETES | PROMETIC BIOSCIENCES INC. (CA) | 2016-04-14 | — | — | WO | disclosed |
| WO-2016054726-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DIABETES | PROMETIC BIOSCIENCES INC. (CA) | 2016-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210085626-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | COL1A1, CCNH, COL2A1 | PTGS2 322/4885CYP3A4 2227/4885TSHR 2754/4885 |
| US-20170312237-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | CCNH, COL1A1, COL2A1 | PTGS2 263/4885CYP3A4 2283/4885TSHR 2935/4885 |
| US-10391073-B2 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | CCNH, COL1A1, COL2A1 | PTGS2 263/4885CYP3A4 2283/4885TSHR 2935/4885 |
| US-10869849-B2 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | COL1A1, CCNH, COL2A1 | PTGS2 322/4885CYP3A4 2227/4885TSHR 2754/4885 |
| US-20170209399-A1 | Substituted Aromatic Compounds and Pharmaceutical Compositions For The Prevention And Treatment Of Diabetes | GPR119, LIPC, INSR | PTGS2 2425/4885CYP3A4 571/4885TSHR 508/4885 |
| US-20200078324-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | COL1A1, COL2A1, CCNH | PTGS2 397/4885CYP3A4 2432/4885TSHR 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.