Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276737 | 0.77 | CA1 (0.35) | CA1CA2CA9CA7CA13 | |
| SCHEMBL4707260 | 0.72 | — | — | |
| SCHEMBL28987461 | 0.68 | — | — | |
| SCHEMBL23067553 | 0.67 | CA1 (0.32) | CA1CA2CA9CA7CA13 | |
| SCHEMBL3259549 | 0.65 | CA1 (0.35) | CA1CA2CA9CA7CA13 | |
| SCHEMBL26864 | 0.64 | — | — | |
| SCHEMBL23688780 | 0.62 | — | — | |
| Ethane SCHEMBL4974014 | 0.61 | CA1 (0.44) | CA1CA2CA9CA7CA13 | |
| Sulfamide SCHEMBL25410596 | 0.61 | CA1 (0.50) | CA1CA2CA9CA7CA13 | |
| Hydrochloric Acid SCHEMBL10876127 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11897905-B2 | Degradable polymers of a cyclic silyl ether and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-02-13 | — | — | US | disclosed |
| US-11752221-B2 | Brush-arm star polymer imaging agents and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | disclosed |
| US-11179710-B2 | Direct palladium-catalyzed aromatic fluorination | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-23 | — | — | US | disclosed |
| US-20210284664-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-09-16 | — | — | US | disclosed |
| US-10918714-B2 | Human iNKT cell activation using glycolipids with altered glycosyl groups | ACADEMIA SINICA (TW) | 2021-02-16 | — | — | US | disclosed |
| US-10815482-B2 | Chiral design | WAVE LIFE SCIENCES LTD. (SG) | 2020-10-27 | — | — | US | disclosed |
| US-20200080083-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-03-12 | — | — | US | disclosed |
| US-10508121-B2 | Cortistatin analogues and syntheses and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-12-17 | — | — | US | disclosed |
| US-10479995-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2019-11-19 | — | — | US | disclosed |
| US-10398781-B2 | Conjugate based systems for controlled drug delivery | SMARTCELLS, INC. (US) | 2019-09-03 | — | — | US | disclosed |
| US-9975872-B2 | Processes for the preparation of (s)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and pharmaceutically acceptable forms thereof | CELGENE CORPORATION (US) | 2018-05-22 | — | — | US | disclosed |
| US-20180064824-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | MERCK SHARP & DOHME CORP. (US) | 2018-03-08 | — | — | US | disclosed |
| US-20180011104-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2018-01-11 | — | — | US | disclosed |
| US-20170349590-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | OXFORD FINANCE LLC | 2017-12-07 | — | — | US | disclosed |
| US-9802922-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170281542-A1 | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-10-05 | — | — | US | disclosed |
| US-20170129876-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2017-05-11 | — | — | US | disclosed |
| US-20170066797-A1 | WITHAFERIN A ANALOGS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2017-03-09 | — | — | US | disclosed |
| US-20170029435-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2017-02-02 | — | — | US | disclosed |
| US-20160193351-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | SMARTCELLS, INC. (US) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10398781-B2 | Conjugate based systems for controlled drug delivery | SI, CSGALNACT1, CD44 | CA1 357/4885CA2 922/4885CA9 263/4885 |
| US-10508121-B2 | Cortistatin analogues and syntheses and uses thereof | CDK9, CDK19, HIF1AN | CA1 759/4885CA2 658/4885CA9 67/4885 |
| US-20170066797-A1 | WITHAFERIN A ANALOGS AND USES THEREOF | CYP51A1, HASPIN, NFATC1 | CA1 2413/4885CA2 2450/4885CA9 1659/4885 |
| US-20180011104-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | MPI, AADAC, PAICS | CA1 2923/4885CA2 3647/4885CA9 1139/4885 |
| US-20170281542-A1 | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | RNMT, NSUN3, IGF2BP3 | CA1 4279/4885CA2 3627/4885CA9 4586/4885 |
| US-11897905-B2 | Degradable polymers of a cyclic silyl ether and uses thereof | SI, ILK, PCNA | CA1 434/4885CA2 2449/4885CA9 753/4885 |
| US-20210284664-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | SI, ILK, PCNA | CA1 434/4885CA2 2449/4885CA9 753/4885 |
| US-11179710-B2 | Direct palladium-catalyzed aromatic fluorination | KRAS, NRAS, DDT | CA1 4015/4885CA2 4719/4885CA9 2564/4885 |
| US-10918714-B2 | Human iNKT cell activation using glycolipids with altered glycosyl groups | UGCG, GALK1, B3GAT3 | CA1 2266/4885CA2 3196/4885CA9 1963/4885 |
| US-20170029435-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | CDK19, CDK9, CDK1 | CA1 902/4885CA2 859/4885CA9 115/4885 |
| US-10479995-B2 | Oligonucleotide compositions and methods thereof | RNGTT, NSUN2, POLRMT | CA1 327/4885CA2 2251/4885CA9 723/4885 |
| US-20170349590-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | SLCO1B1, SLCO2B1, ABCB11 | CA1 2442/4885CA2 2342/4885CA9 163/4885 |
| US-20180064824-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | SI, CSGALNACT1, CD44 | CA1 357/4885CA2 922/4885CA9 263/4885 |
| US-20200080083-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | RNGTT, NSUN2, POLRMT | CA1 327/4885CA2 2251/4885CA9 723/4885 |
| US-20160193351-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | SI, CSGALNACT1, CD44 | CA1 357/4885CA2 922/4885CA9 263/4885 |
| US-11752221-B2 | Brush-arm star polymer imaging agents and uses thereof | RHOC, BRAP, PAM | CA1 420/4885CA2 804/4885CA9 237/4885 |
| US-20170129876-A1 | UREA DERIVATIVES AND USES THEREOF | UACA, RB1, FLT1 | CA1 3370/4885CA2 2437/4885CA9 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.