Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 known ✓ | Q92731 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466993 | 1.00 | MAPT (0.54) | MAPTKMT2ASMN1; SMN2SLC6A3ESR1 | |
| Potassium Ion SCHEMBL5974784 | 0.97 | MAPT (0.54) | MAPTKMT2ASMN1; SMN2SLC6A3ESR1 | |
| SCHEMBL9726282 | 0.88 | SLC6A3 (0.51) | MAPTKMT2ASLC6A3POLBTDP1 | |
| SCHEMBL9726276 | 0.84 | SMN1; SMN2 (0.48) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL5815925 | 0.83 | KMT2A (0.58) | MAPTKMT2ASMN1; SMN2SLC6A3ESR1 | |
| SCHEMBL38811 | 0.83 | KMT2A (0.58) | MAPTKMT2ASMN1; SMN2SLC6A3ESR1 | |
| SCHEMBL31098906 | 0.83 | KMT2A (0.58) | MAPTKMT2ASMN1; SMN2SLC6A3ESR1 | |
| SCHEMBL9726303 | 0.82 | LMNA (0.54) | MAPTKMT2ASMN1; SMN2ESR1MEN1 | |
| SCHEMBL27791528 | 0.81 | MAPT (0.56) | MAPTKMT2ASMN1; SMN2SLC6A3ESR1 | |
| SCHEMBL11242849 | 0.81 | KMT2A (0.56) | MAPTKMT2ASMN1; SMN2SLC6A3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430586-B | Hydrogen peroxide booster system for enhanced tooth whitening | 高露洁-棕榄公司 | 2021-07-23 | — | — | CN | claimed |
| US-10829723-B2 | Devices for removing oxidizable stains and methods for the same | Henkel IP & Holding GmbH (DE) | 2020-11-10 | — | — | US | claimed |
| US-20200297594-A1 | Hydrogen Peroxide Booster System for Enhanced Teeth Whitening | COLGATE-PALMOLIVE COMPANY (US) | 2020-09-24 | — | — | US | claimed |
| US-20180369087-A1 | Hydrogen Peroxide Booster System for Enhanced Teeth Whitening | COLGATE-PALMOLIVE COMPANY (US) | 2018-12-27 | — | — | US | claimed |
| EP-3383503-A1 | HYDROGEN PEROXIDE BOOSTER SYSTEM FOR ENHANCED TEETH WHITENING | Colgate-Palmolive Company (US) | 2018-10-10 | — | — | EP | claimed |
| WO-2017105455-A1 | HYDROGEN PEROXIDE BOOSTER SYSTEM FOR ENHANCED TEETH WHITENING | COLGATE-PALMOLIVE COMPANY (US) | 2017-06-22 | — | — | WO | claimed |
| US-8431519-B2 | Co-granulates of bleach activator-peroxide compounds | OCI CHEMICAL CORP. (US) | 2013-04-30 | — | — | US | claimed |
| US-20100207062-A1 | CO-GRANULATES OF BLEACH ACTIVATOR-PEROXIDE COMPOUNDS | OCI CHEMICAL CORPORATION (US) | 2010-08-19 | — | — | US | claimed |
| US-7709437-B2 | Co-granulates of bleach activator-peroxide compounds | OCI CHEMICAL CORP. (US) | 2010-05-04 | — | — | US | claimed |
| EP-2021454-A1 | CO-GRANULATES OF BLEACH ACTIVATOR-PEROXIDE COMPOUNDS | OCI Chemical Corporation (US) | 2009-02-11 | — | — | EP | claimed |
| WO-1995013353-A1 | ACTIVATION OF BLEACH PRECURSORS WITH IMINE QUATERNARY SALTS | UNILEVER N.V. (NL) | 1995-05-18 | — | — | WO | claimed |
| US-5360569-A | Peroxygen bleaches with oxygen transfer agent of isoquinolium compound and forming percarboxylic, percarbonic acid or perimidic acid | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1994-11-01 | — | — | US | claimed |
| EP-0341947-B1 | Enzymatic detergent and bleaching composition | UNILEVER PLC (GB) | 1994-08-31 | — | — | EP | claimed |
| WO-1994010284-A1 | GRANULAR DETERGENTS WITH PROTEASE ENZYME AND BLEACH | THE PROCTER & GAMBLE COMPANY (US) | 1994-05-11 | — | — | WO | claimed |
| US-5202045-A | S-shaped detergent laminate | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1993-04-13 | — | — | US | claimed |
| US-5055217-A | Mixture of bleach precursor, binder and sugar; high cleaning performance against stains | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1991-10-08 | — | — | US | claimed |
| US-5047163-A | Low Temperature Bleaching Composition Containing A Peroxygen Compound, A Sulfonimine Oxygen Transfer Agent Activator And A! Bleach Percursor | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1991-09-10 | — | — | US | claimed |
| US-5030380-A | Bleaching | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1991-07-09 | — | — | US | claimed |
| EP-0405628-A2 | Polymeric electrolyte-hydrogen peroxide adducts | UNILEVER N.V. (NL) | 1991-01-02 | — | — | EP | claimed |
| US-4927559-A | SODIUM PERBORATE, SODIUM BENZOYLOXYBENZENE SULFONATE | LEVER BROTHERS COMPANY (US) | 1990-05-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200297594-A1 | Hydrogen Peroxide Booster System for Enhanced Teeth Whitening | GPX4, GPX1, PRDX3 | ESR2 1936/4885MAPT 2625/4885KMT2A 812/4885 |
| US-20180369087-A1 | Hydrogen Peroxide Booster System for Enhanced Teeth Whitening | CAT, GPX4, LPO | ESR2 1770/4885MAPT 2478/4885KMT2A 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.