SCHEMBL18044318

SCHEMBL18044318

Cc1cccc(C)c1-c1ccc(N=Nc2cc(S(=O)(=O)O)c3ccccc3c2N)cn1

nearest known ligand 0.79

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ SENP2 Q9HC62 4/20 0.66
▸ SENP1 Q9P0U3 4/20 0.66
▸ SUMO2 P61956 3/20 0.66
▸ SUMO1 P63165 3/20 0.66
▸ SENP7 Q9BQF6 3/20 0.66
▸ SENP3 Q9H4L4 2/20 0.66
▸ MEN1 O00255 1/20 0.63
▸ ALDH1A1 P00352 1/20 0.63
▸ APP P05067 1/20 0.63
▸ MAPT P10636 1/20 0.63
▸ THRB P10828 1/20 0.63
▸ HPGD P15428 1/20 0.63
▸ ALOX12 P18054 1/20 0.63
▸ SNCA P37840 1/20 0.63
▸ RECQL P46063 1/20 0.63
▸ BLM P54132 1/20 0.63
▸ KMT2A Q03164 1/20 0.63
▸ TDP1 Q9NUW8 1/20 0.63
▸ SLC7A11 Q9UPY5 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29697200 1.00 SENP2 (0.66) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL15120234 1.00 SENP2 (0.66) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL14988780 0.99 SENP2 (0.65) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL14988778 0.99 SENP2 (0.65) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL15120146 0.92 SENP2 (0.67) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL29697126 0.92 SENP2 (0.67) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL18044194 0.92 SENP2 (0.67) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL18044220 0.91 SENP2 (0.63) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL29697069 0.91 SENP2 (0.63) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL15120172 0.91 SENP2 (0.63) SENP2SENP1SUMO2SUMO1SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250057823-A1 COMPOSITION FOR IMPROVING CARDIAC FUNCTION KYOTO UNIVERSITY (JP) 2025-02-20 — — US claimed
EP-4454648-A1 COMPOSITION FOR IMPROVING HEART FUNCTION Kyoto University (JP) 2024-10-30 — — EP claimed
US-20240216397-A1 COMPOSITION FOR AMELIORATING SKIN TISSUE ABNORMALITY KYOTO UNIVERSITY (JP) 2024-07-04 — — US claimed
US-12011438-B2 Composition for protecting cardiomyocyte KYOTO UNIVERSITY (JP) 2024-06-18 — — US claimed
EP-4331589-A1 COMPOSITION FOR AMELIORATING ABNORMALITY OF SKIN TISSUE Kyoto University (JP) 2024-03-06 — — EP claimed
WO-2023140242-A1 COMPOSITION FOR PROTECTING TISSUE ISOLATED FROM LIVING BODY 国立大学法人京都大学 2023-07-27 — — WO claimed
WO-2023120704-A1 COMPOSITION FOR IMPROVING HEART FUNCTION 国立大学法人京都大学 2023-06-29 — — WO claimed
US-20220401461-A1 Pharmaceutical Composition for Protecting Cartilage KYOTO UNIVERSITY (JP) 2022-12-22 — — US claimed
WO-2022230949-A1 COMPOSITION FOR AMELIORATING ABNORMALITY OF SKIN TISSUE 国立大学法人京都大学 2022-11-03 — — WO claimed
EP-4049724-A1 PHARMACEUTICAL COMPOSITION FOR PROTECTING CARTILAGE Kyoto University (JP) 2022-08-31 — — EP claimed
EP-3733177-A1 COMPOSITION FOR CORNEAL PROTECTION Kyoto University (JP) 2020-11-04 — — EP claimed
CN-111757733-A Composition for protecting cornea 国立大学法人京都大学 2020-10-09 — — CN claimed
WO-2020027137-A1 MEDICINE COMPOSITION FOR TREATING CEREBRAL INFARCTION 国立大学法人京都大学 2020-02-06 — — WO claimed
WO-2019203176-A1 PHARMACEUTICAL COMPOSITION FOR PROTECTING MYOCARDIAL CELLS 国立大学法人京都大学 2019-10-24 — — WO claimed
EP-3042658-B1 MEDICINAL COMPOSITION IMPROVING LEPTIN RESISTANCE UNIV KYOTO (JP) 2019-01-16 — — EP claimed
US-9931351-B2 Method for improving leptin resistance KYOTO UNIVERSITY (JP) 2018-04-03 — — US claimed
US-9782420-B2 Method for treating eye diseases KYOTO UNIVERSITY (JP) 2017-10-10 — — US claimed
US-9573887-B2 Naphthalene derivative DAITO CHEMIX CORPORATION (JP) 2017-02-21 — — US claimed
US-20160303144-A1 Medicinal Composition Improving Leptin Resistance KYOTO UNIVERSITY (JP) 2016-10-20 — — US claimed
EP-2599771-B1 NAPHTHALENE DERIVATIVE DAITO CHEMIX CORP (JP) 2016-09-14 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057823-A1 COMPOSITION FOR IMPROVING CARDIAC FUNCTION TNNI3, NPPA, TNNT2 SENP2 3538/4885SENP1 2852/4885SUMO2 4148/4885
US-12011438-B2 Composition for protecting cardiomyocyte TNNI3, TNNT2, TNNC1 SENP2 2730/4885SENP1 1865/4885SUMO2 2295/4885
US-20160303144-A1 Medicinal Composition Improving Leptin Resistance LIPC, ADIPOR1, GPR119 SENP2 3218/4885SENP1 3152/4885SUMO2 4540/4885
US-20220401461-A1 Pharmaceutical Composition for Protecting Cartilage COL2A1, MATR3, COL1A1 SENP2 2405/4885SENP1 1400/4885SUMO2 2757/4885
US-20240216397-A1 COMPOSITION FOR AMELIORATING SKIN TISSUE ABNORMALITY CUTA, FABP4, MMP13 SENP2 3876/4885SENP1 3680/4885SUMO2 3580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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