SCHEMBL18532015

SCHEMBL18532015

N=C(NN)NCCC[C@H](N)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OTC P00480 1/20 0.53
DDAH1 O94760 3/20 0.46
GSR P00390 2/20 0.46
NOS2 P35228 3/20 0.44
NOS3 P29474 2/20 0.44
NOS1 P29475 2/20 0.44
ARG2 P78540 4/20 0.42
ARG1 P05089 3/20 0.42
CYP1A2 P05177 2/20 0.41
GLA P06280 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
APEX1 P27695 1/20 0.41
CYP2C19 P33261 1/20 0.41
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIK1 P39086 1/20 0.39
GRM5 P41594 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2757544 0.95 GSR (0.48) OTCDDAH1GSRNOS2NOS3
SCHEMBL9845047 0.95 GSR (0.48) OTCDDAH1GSRNOS2NOS3
SCHEMBL13059111 0.88 OTC (0.51) OTCDDAH1GSRNOS2NOS3
SCHEMBL448333 0.86 OTC (0.53) OTCDDAH1GSRNOS2NOS3
Tilarginine SCHEMBL12028766 0.84 OTC (0.51) OTCDDAH1GSRNOS2NOS3
Tilarginine SCHEMBL6370536 0.84 OTC (0.51) OTCDDAH1GSRNOS2NOS3
Tilarginine SCHEMBL315843 0.84 OTC (0.51) OTCDDAH1GSRNOS2NOS3
SCHEMBL21089964 0.84 OTC (0.51) OTCDDAH1GSRNOS2NOS3
SCHEMBL24451312 0.83 OTC (0.50) OTCDDAH1GSRNOS2NOS3
SCHEMBL8730134 0.83 NOD1 (0.52) OTCDDAH1GSRNOS2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MED LTD (GB) 2026-05-07 US disclosed
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof GENEFRONTIER CORPORATION (JP) 2026-03-03 US disclosed
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-02-05 US disclosed
EP-4598592-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT Owlstone Medical Limited (GB) 2025-08-13 EP disclosed
CN-120152745-A Compounds and their use for detecting diseases in exhaled breath of a subject 奥斯通医疗有限公司 2025-06-13 CN disclosed
US-20240325561-A1 PEGYLATED DRUG-LINKERS FOR IMPROVED LIGAND-DRUG CONJUGATE PHARMACOKINETICS SEAGEN INC (US) 2024-10-03 US disclosed
US-20240261427-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. 2024-08-08 US disclosed
US-20240245796-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. 2024-07-25 US disclosed
US-20240207429-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME WILMINGTON TRUST, NATIONAL ASSOCIATION 2024-06-27 US disclosed
US-20240207418-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. 2024-06-27 US disclosed
EP-4103587-A1 CORONA VIRUS VACCINE Immunor AS (NO) 2022-12-21 EP disclosed
EP-4074328-A1 INTERMEDIATES OF CONJUGATES OF QUATERNIZED TUBULYSIN COMPOUNDS Seagen Inc. (US) 2022-10-19 EP disclosed
US-20220296584-A1 Membrane Active Molecules KNOWLEDGE PHARMACEUTICALS INC. 2022-09-22 US disclosed
EP-4043076-A1 CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF GeneFrontier Corporation (JP) 2022-08-17 EP disclosed
US-20220226482-A1 CONJUGATES OF QUATERNIZED TUBULYSIN COMPOUNDS SEAGEN INC (US) 2022-07-21 US disclosed
EP-3973997-A1 MEMBRANE ACTIVE MOLECULES Branequest, Inc. (US) 2022-03-30 EP disclosed
EP-3383420-B1 CONJUGATES OF QUATERNIZED TUBULYSIN COMPOUNDS SEAGEN INC (US) 2022-03-23 EP disclosed
US-20220072146-A1 PEGYLATED DRUG-LINKERS FOR IMPROVED LIGAND-DRUG CONJUGATE PHARMACOKINETICS SEAGEN INC (US) 2022-03-10 US disclosed
US-9574190-B2 Screening method for peptide binding to target molecule in pH-dependent manner THE UNIVERSITY OF TOKYO (JP) 2017-02-21 US disclosed
CN-1326785-A Anti-cancer medicine composition KONG QINGZHONG (CN) 2001-12-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME CSGALNACT1, SLC43A1, OSTC OTC 955/4885DDAH1 679/4885GSR 2923/4885
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof CXCL10, MLX, MICA OTC 3651/4885DDAH1 3101/4885GSR 4749/4885
US-20240207418-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 OTC 2274/4885DDAH1 2586/4885GSR 1896/4885
US-20220072146-A1 PEGYLATED DRUG-LINKERS FOR IMPROVED LIGAND-DRUG CONJUGATE PHARMACOKINETICS EGFR, HDGF, CD47 OTC 1200/4885DDAH1 1163/4885GSR 1502/4885
US-20220226482-A1 CONJUGATES OF QUATERNIZED TUBULYSIN COMPOUNDS LCK, UACA, TEKT1 OTC 2659/4885DDAH1 3074/4885GSR 4646/4885
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT BRCA1, L3MBTL1, LMNA OTC 1408/4885DDAH1 495/4885GSR 1876/4885
US-20220296584-A1 Membrane Active Molecules GABRP, GRIN3A, GRIN2A OTC 645/4885DDAH1 3208/4885GSR 869/4885
US-20240207429-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 OTC 2274/4885DDAH1 2586/4885GSR 1896/4885
US-20240325561-A1 PEGYLATED DRUG-LINKERS FOR IMPROVED LIGAND-DRUG CONJUGATE PHARMACOKINETICS EGFR, HDGF, CD47 OTC 1199/4885DDAH1 1166/4885GSR 1501/4885
US-20240261427-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 OTC 2274/4885DDAH1 2586/4885GSR 1896/4885
US-20240245796-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 OTC 2274/4885DDAH1 2586/4885GSR 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.