SCHEMBL1880376

SCHEMBL1880376

CCCN(CC)C(=O)CCl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.44
CA9 Q16790 4/20 0.44
CA2 P00918 3/20 0.44
ALDH1A1 P00352 4/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
LMNA P02545 1/20 0.41
CA1 P00915 3/20 0.39
RAB9A P51151 3/20 0.39
TDP1 Q9NUW8 2/20 0.38
NPC1 O15118 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TP53 P04637 2/20 0.38
KDM4E B2RXH2 1/20 0.37
MITF O75030 1/20 0.37
HTT P42858 1/20 0.37
EGFR P00533 1/20 0.37
ERBB2 P04626 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL781780 0.90 ALDH1A1 (0.52) CA12CA9CA2ALDH1A1HPGD
SCHEMBL224316 0.85
SCHEMBL10348297 0.84 ALDH1A1 (0.43) CA12CA9CA2ALDH1A1HPGD
SCHEMBL5204543 0.81 CA12 (0.44) CA12CA9CA2ALDH1A1HPGD
SCHEMBL24162327 0.80 LMNA (0.41) CA12CA9CA2ALDH1A1HPGD
SCHEMBL31457896 0.80 CA12 (0.40) CA12CA9CA2ALDH1A1HPGD
SCHEMBL10489425 0.80 CA12 (0.48) CA12CA9CA2ALDH1A1HPGD
SCHEMBL19674066 0.79 MLYCD (0.43) ALDH1A1HPGDTSHRLMNARAB9A
SCHEMBL12339144 0.78 CA12 (0.46) CA12CA9CA2ALDH1A1HPGD
SCHEMBL13317119 0.78 ALDH1A1 (0.56) CA12CA9CA2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS KULEON LLC (US) 2025-11-06 US disclosed
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same Kuleon, LLC (US) 2025-10-14 US disclosed
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME KULEON LLC (US) 2025-09-11 US disclosed
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression Kuleon, LLC (US) 2025-07-01 US disclosed
US-12275701-B2 Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators Kuleon, LLC (US) 2025-04-15 US disclosed
US-20250091991-A1 MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION Kuleon, LLC (US) 2025-03-20 US disclosed
US-12187678-B2 Methods of treating psychological disorders through the administration of serotonin 5-HT2C receptor modulators Kuleon, LLC (US) 2025-01-07 US disclosed
US-20240343690-A1 Neuroplastogens and Non-Hallucinogenic Serotonin 5-HT2A Receptor Modulators KULEON LLC (US) 2024-10-17 US disclosed
EP-4384172-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME Kuleon LLC (US) 2024-06-19 EP disclosed
US-7939689-B2 Short-acting sedative hypnotic agents for anesthesia and sedation THERAVANCE, INC. (US) 2011-05-10 US disclosed
US-20090253787-A1 SHORT-ACTING SEDATIVE HYPNOTIC AGENTS FOR ANESTHESIA AND SEDATION THERAVANCE, INC. (US) 2009-10-08 US disclosed
US-7514425-B2 Short-acting sedative hypnotic agents for anesthesia and sedation THERAVANCE, INC. (US) 2009-04-07 US disclosed
US-20060116424-A1 Short-acting sedative hypnotic agents for anesthesia and sedation THERAVANCE BIOPHARMA R&D IP, LLC 2006-06-01 US disclosed
US-7015346-B2 Short-acting sedative hypnotic agents for anesthesia and sedation THERAVANCE, INC. (US) 2006-03-21 US disclosed
US-20050113364-A1 Short-acting sedative hypnotic agents for anesthesia and sedation THERAVANCE BIOPHARMA R&D IP, LLC 2005-05-26 US disclosed
US-6887866-B2 Short-acting sedative hypnotic agents for anesthesia and sedation THERAVANCE, INC. (US) 2005-05-03 US disclosed
EP-1509492-A2 SHORT-ACTING SEDATIVE HYPNOTIC AGENTS FOR ANESTHESIA AND SEDATION Theravance, Inc. (US) 2005-03-02 EP disclosed
WO-2004037750-A2 SHORT-ACTING SEDATIVE HYPNOTIC AGENTS FOR ANESTHESIA AND SEDATION THERAVANCE, INC. (US) 2004-05-06 WO disclosed
US-20030153554-A1 Short-acting sedative hypnotic agents for anesthesia and sedation THERAVANCE BIOPHARMA R&D IP, LLC 2003-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 CA12 2458/4885CA9 1661/4885CA2 2151/4885
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME HTR7, HTR2C, HTR1A CA12 4829/4885CA9 4826/4885CA2 4598/4885
US-20090253787-A1 SHORT-ACTING SEDATIVE HYPNOTIC AGENTS FOR ANESTHESIA AND SEDATION GABRA5, GABRA6, GABRA2 CA12 2258/4885CA9 1524/4885CA2 687/4885
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same HTR7, HTR2C, HTR1A CA12 4829/4885CA9 4826/4885CA2 4598/4885
US-12275701-B2 Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators HTR2A, HTR2C, HTR1A CA12 4277/4885CA9 4869/4885CA2 4215/4885
US-20050113364-A1 Short-acting sedative hypnotic agents for anesthesia and sedation GABRA5, GABRA6, GABRA2 CA12 2258/4885CA9 1524/4885CA2 687/4885
US-12187678-B2 Methods of treating psychological disorders through the administration of serotonin 5-HT2C receptor modulators HTR2C, HTR2A, HTR3B CA12 4452/4885CA9 4870/4885CA2 3748/4885
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS HTR2A, HTR2C, HTR3A CA12 4068/4885CA9 4864/4885CA2 3924/4885
US-20030153554-A1 Short-acting sedative hypnotic agents for anesthesia and sedation GABRA5, GABRA6, GABRA2 CA12 2258/4885CA9 1524/4885CA2 687/4885
US-20060116424-A1 Short-acting sedative hypnotic agents for anesthesia and sedation GABRA5, GABRA6, GABRA2 CA12 2258/4885CA9 1524/4885CA2 687/4885
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression HTR2A, HTR2C, HTR3A CA12 4149/4885CA9 4795/4885CA2 2724/4885
US-20240343690-A1 Neuroplastogens and Non-Hallucinogenic Serotonin 5-HT2A Receptor Modulators HTR2A, HTR2C, HTR1A CA12 4277/4885CA9 4869/4885CA2 4215/4885
US-20250091991-A1 MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION HTR2A, HTR2C, HTR3A CA12 4149/4885CA9 4795/4885CA2 2724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.