SCHEMBL18918484

SCHEMBL18918484

CNC(=O)[C@@]1(N2CCCCC2)CC=CCC1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.33
CYP3A4 P08684 2/20 0.33
HSD11B1 P28845 1/20 0.33
HSD11B2 P80365 1/20 0.33
LMNA P02545 2/20 0.32
GAA P10253 2/20 0.32
ALDH1A1 P00352 4/20 0.32
CYP2C19 P33261 2/20 0.32
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
DUSP3 P51452 1/20 0.30
PTPN5 P54829 1/20 0.30
PTPN11 Q06124 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6175645 0.72 HSD11B1 (0.38) SMN1; SMN2CYP3A4HSD11B1HSD11B2LMNA
Hydrochloric Acid SCHEMBL4611963 0.71 HSD11B1 (0.37) SMN1; SMN2CYP3A4HSD11B1HSD11B2LMNA
SCHEMBL4941740 0.68 HSD11B1 (0.35) SMN1; SMN2CYP3A4HSD11B1HSD11B2LMNA
Formic Acid SCHEMBL4941735 0.68 HSD11B1 (0.35) SMN1; SMN2CYP3A4HSD11B1HSD11B2KDM4E
SCHEMBL27485221 0.66 CYP3A4 (0.33) SMN1; SMN2CYP3A4
SCHEMBL15942311 0.62 HPGD (0.34) GAAALDH1A1
SCHEMBL232028 0.61 NPSR1 (0.39) CYP3A4HSD11B1HSD11B2GAAALDH1A1
SCHEMBL28053497 0.61 HSD11B1 (0.40) SMN1; SMN2HSD11B1HSD11B2LMNAGAA
SCHEMBL14597531 0.60 ALDH1A1 (0.37) HSD11B1HSD11B2GAAALDH1A1TP53
SCHEMBL28481309 0.60 ALDH1A1 (0.37) HSD11B1HSD11B2GAAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents COLABS INT'L CORP. (US) 2024-03-28 US claimed
US-20170216164-A1 Compositions Containing a Flexible Derived Capsule with An Active Agent CoLabs International Corporation (US) 2017-08-03 US claimed
US-20240415074-A1 REPELLENT DELIVERY DEVICE WITH GLYCERIN SOAP BODY AND RELATED METHODS RADICAL AG TECH, INC. 2024-12-19 US disclosed
US-12114610-B2 Repellent delivery device with glycerin soap body and related methods RADICAL AG TECH, INC. (US) 2024-10-15 US disclosed
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents COLABS INT'L CORP. (US) 2024-03-28 US disclosed
US-11839674-B2 Compositions comprising silicon dioxide-based particles including one or more agents CoLabs International Corporation (US) 2023-12-12 US disclosed
US-11707421-B2 Compositions containing a flexible derived capsule with an active agent COLABS INT'L CORP. (US) 2023-07-25 US disclosed
US-20230113098-A1 Compositions Containing a Capsule with an Agent COLABS INT'L CORP. (US) 2023-04-13 US disclosed
US-11491088-B2 Compositions containing a capsule with a moisturizing agent CoLabs International Corporation (US) 2022-11-08 US disclosed
US-20210176924-A1 REPELLENT DELIVERY DEVICE WITH GLYCERIN SOAP BODY AND RELATED METHODS RADICAL AG TECH, INC. 2021-06-17 US disclosed
US-10322301-B2 Compositions containing a cellulose derived capsule with a sunscreen active agent CoLabs International Corporation (US) 2019-06-18 US disclosed
US-20170216164-A1 Compositions Containing a Flexible Derived Capsule with An Active Agent CoLabs International Corporation (US) 2017-08-03 US disclosed
US-20170216165-A1 Compositions Containing a Capsule with a Moisturizing Agent CoLabs International Corporation (US) 2017-08-03 US disclosed
US-20170157021-A1 Compositions Containing a Cellulose Derived Capsule with a Sunscreen Active Agent CoLabs International Corporation (US) 2017-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11707421-B2 Compositions containing a flexible derived capsule with an active agent CUTA, LIPE, LIPA SMN1; SMN2 3151/4885CYP3A4 3480/4885HSD11B1 3460/4885
US-20170216164-A1 Compositions Containing a Flexible Derived Capsule with An Active Agent CUTA, LIPE, LIPA SMN1; SMN2 3151/4885CYP3A4 3480/4885HSD11B1 3460/4885
US-20170157021-A1 Compositions Containing a Cellulose Derived Capsule with a Sunscreen Active Agent CUTA, ACMSD, TYR SMN1; SMN2 3220/4885CYP3A4 2323/4885HSD11B1 1697/4885
US-20230113098-A1 Compositions Containing a Capsule with an Agent LIPA, CUTA, FABP4 SMN1; SMN2 2885/4885CYP3A4 3235/4885HSD11B1 3514/4885
US-20170216165-A1 Compositions Containing a Capsule with a Moisturizing Agent CUTA, LIPA, PLIN5 SMN1; SMN2 3137/4885CYP3A4 3613/4885HSD11B1 3463/4885
US-11491088-B2 Compositions containing a capsule with a moisturizing agent CUTA, LIPA, PLIN5 SMN1; SMN2 3137/4885CYP3A4 3613/4885HSD11B1 3463/4885
US-10322301-B2 Compositions containing a cellulose derived capsule with a sunscreen active agent CUTA, ACMSD, TYR SMN1; SMN2 3220/4885CYP3A4 2323/4885HSD11B1 1697/4885
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents MSN, LIPE, CUTA SMN1; SMN2 937/4885CYP3A4 3904/4885HSD11B1 3236/4885
US-11839674-B2 Compositions comprising silicon dioxide-based particles including one or more agents MSN, LIPE, CUTA SMN1; SMN2 936/4885CYP3A4 3902/4885HSD11B1 3215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.