Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 4/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 1/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670385 | 0.90 | MPL (0.44) | FAAHPIM1GSK3BMAPK14FYN | |
| SCHEMBL19670164 | 0.90 | GSK3B (0.40) | PIM1GSK3BMAPK14IRAK4SLC5A1 | |
| SCHEMBL19670589 | 0.89 | HTR2C (0.42) | ABL1FAAHFYNHTR2C | |
| SCHEMBL19670257 | 0.89 | HPGDS (0.38) | PIM1GSK3BMAPK14HPGDSDYRK1A | |
| SCHEMBL19670590 | 0.85 | IRAK4 (0.41) | ABL1PIM1FYNKCNH2PIM2 | |
| SCHEMBL19670252 | 0.85 | THRB (0.38) | — | |
| SCHEMBL19669985 | 0.85 | KARS1 (0.43) | ABL1FAAHGSK3BFLT3DYRK1A | |
| SCHEMBL19365492 | 0.85 | MTOR (0.36) | FAAHKCNH2 | |
| SCHEMBL19365562 | 0.83 | MTOR (0.41) | FAAHGSK3BDYRK1A | |
| SCHEMBL19670238 | 0.83 | TRPA1 (0.38) | ABL1PIM1FYNFLT3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |