Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856960 | 0.86 | PLA2G10 (0.38) | NOD2NOD1CCR2MCL1 | |
| SCHEMBL19856991 | 0.83 | SLC6A7 (0.37) | LMNANOD2NOD1 | |
| SCHEMBL19856988 | 0.83 | NOD2 (0.41) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL19856992 | 0.81 | CCR2 (0.34) | ALDH1A1CCR2 | |
| SCHEMBL19856905 | 0.81 | BTK (0.38) | NOD2NOD1MCL1 | |
| SCHEMBL19856929 | 0.80 | CCR2 (0.35) | LMNACCR2 | |
| SCHEMBL19856981 | 0.80 | SIRT3 (0.38) | ALDH1A1LMNANOD2NOD1CA12 | |
| SCHEMBL19856907 | 0.80 | HCRTR1 (0.33) | NOD2NOD1 | |
| SCHEMBL19856935 | 0.79 | PARP10 (0.40) | — | |
| SCHEMBL19856933 | 0.79 | HPGD (0.36) | ALDH1A1NOD2NOD1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |