Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856910 | 0.93 | HCRTR2 (0.37) | HCRTR2HCRTR1MEN1KMT2A | |
| SCHEMBL19856933 | 0.89 | HPGD (0.36) | HCRTR2HCRTR1NOD2NOD1SPR | |
| SCHEMBL19856907 | 0.88 | HCRTR1 (0.33) | HCRTR2HCRTR1NOD2NOD1SPR | |
| SCHEMBL19856988 | 0.86 | NOD2 (0.41) | MAPTNOD2NOD1MEN1KMT2A | |
| SCHEMBL19856975 | 0.85 | SMN1; SMN2 (0.34) | MAPTMEN1POLBKMT2AAHR | |
| SCHEMBL19856981 | 0.83 | SIRT3 (0.38) | NOD2NOD1MEN1KMT2ALMNA | |
| SCHEMBL19856992 | 0.83 | CCR2 (0.34) | MEN1KMT2ASPRGAA | |
| SCHEMBL19856960 | 0.83 | PLA2G10 (0.38) | NOD2NOD1 | |
| SCHEMBL19856929 | 0.82 | CCR2 (0.35) | HCRTR2HCRTR1LMNA | |
| SCHEMBL19856957 | 0.81 | AVPR1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |