Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.53 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983923 | 0.78 | GPR84 (0.51) | — | |
| SCHEMBL2953504 | 0.71 | KDM4E (0.60) | MEN1KMT2AKDM4E | |
| SCHEMBL19983776 | 0.71 | CHRNB2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL8577619 | 0.70 | SMN1; SMN2 (0.70) | HSD17B1HSD17B2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL7807902 | 0.70 | BRD4 (0.54) | AKT1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19983869 | 0.70 | MMP2 (0.46) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL3786463 | 0.69 | NQO2 (0.73) | HSD17B1HSD17B2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL19984002 | 0.68 | CHRNB2 (0.51) | MEN1KMT2ANTRK1 | |
| SCHEMBL19984287 | 0.68 | MAPT (0.45) | AAK1MAPT | |
| SCHEMBL19984159 | 0.68 | SCN9A (0.36) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |