Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161268 | 0.83 | ACHE (0.36) | KDM4ELMNAMEN1KMT2AAURKA | |
| SCHEMBL20161209 | 0.80 | AURKA (0.40) | POLBKDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL20149081 | 0.78 | KDM4E (0.38) | POLBKDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL20161291 | 0.77 | LMNA (0.39) | POLBKDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL20161113 | 0.77 | RPS6KB1 (0.41) | KDM4ELMNAHTTMEN1KMT2A | |
| SCHEMBL20161118 | 0.75 | CSNK1D (0.46) | POLBKDM4ESMN1; SMN2MAPK1HTT | |
| SCHEMBL20161518 | 0.74 | CASP6 (0.43) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20161335 | 0.73 | KDM4E (0.37) | POLBKDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL20161301 | 0.73 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2TSHRHTTMEN1 | |
| SCHEMBL20161336 | 0.67 | ALDH1A1 (0.39) | POLBKDM4ELMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089330-A2 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |