SCHEMBL20487515

SCHEMBL20487515

NCn1cc([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.48
SLC28A1 O00337 1/20 0.42
SLC28A2 O43868 1/20 0.42
SLC29A1 Q99808 1/20 0.42
SLC28A3 Q9HAS3 1/20 0.42
TK2 O00142 2/20 0.42
P2RY2 P41231 1/20 0.42
UMPS P11172 1/20 0.38
SLC5A2 P31639 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GMNN O75496 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26236136 1.00 PYGM (0.48) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30765011 0.90 PYGM (0.44) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15798509 0.90 PYGM (0.47) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL12245097 0.88 PYGM (0.42) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL12667528 0.88 PYGM (0.42) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL12223730 0.88 PYGM (0.42) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15810684 0.88 PYGM (0.44) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30991676 0.88 P2RY2 (0.53) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15798317 0.87 PYGM (0.45) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15810644 0.87 PYGM (0.45) PYGMSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078356-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY ARCTURUS THERAPEUTICS INC (US) 2026-03-19 US claimed
US-12398379-B2 Compositions and methods for treating ornithine transcarbamylase deficiency ARCTURUS THERAPEUTICS, INC. (US) 2025-08-26 US claimed
US-20240002815-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY ARCTURUS THERAPEUTICS, INC. 2024-01-04 US claimed
US-11685906-B2 Compositions and methods for treating ornithine transcarbamylase deficiency ARCTURUS THERAPEUTICS, INC. (US) 2023-06-27 US claimed
US-20260078356-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY ARCTURUS THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260069677-A1 COMPOSITIONS AND METHODS FOR INDUCING IMMUNE RESPONSES ARCTURUS THERAPEUTICS INC (US) 2026-03-12 US disclosed
US-20260015641-A1 METHODS FOR IN VITRO TRANSCRIPTION ARCTURUS THERAPEUTICS INC (US) 2026-01-15 US disclosed
US-12509698-B2 Synthesis and structure of high potency RNA therapeutics ARCTURUS THERAPEUTICS, INC. (US) 2025-12-30 US disclosed
EP-4658307-A2 METHODS AND COMPOSITIONS FOR QUADRIVALENT INFLUENZA VACCINE Arcturus Therapeutics, Inc. (US) 2025-12-10 EP disclosed
US-12398379-B2 Compositions and methods for treating ornithine transcarbamylase deficiency ARCTURUS THERAPEUTICS, INC. (US) 2025-08-26 US disclosed
US-12390524-B2 Compositions and methods for inducing immune responses ARCTURUS THERAPEUTICS, INC. (US) 2025-08-19 US disclosed
EP-3630964-B1 THERAPEUTICS FOR GLYCOGEN STORAGE DISEASE TYPE III ULTRAGENYX PHARMACEUTICAL INC (US) 2025-08-13 EP disclosed
US-20210290752-A1 COMPOSITIONS AND METHODS FOR INDUCING IMMUNE RESPONSES ARCTURUS THERAPEUTICS, INC. 2021-09-23 US disclosed
US-20210290756-A1 CORONAVIRUS VACCINE COMPOSITIONS AND METHODS ARCTURUS THERAPEUTICS, INC. 2021-09-23 US disclosed
WO-2021183564-A1 COMPOSITIONS AND METHODS FOR INDUCING IMMUNE RESPONSES ARCTURUS THERAPEUTICS, INC. (US) 2021-09-16 WO disclosed
US-20210284974-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORNITHINE TRANSCARBAMYLASE DEFICIENCY ARCTURUS THERAPEUTICS, INC. 2021-09-16 US disclosed
US-20200297634-A1 METHOD OF MAKING LIPID-ENCAPSULATED RNA NANOPARTICLES ARCTURUS THERAPEUTICS, INC. 2020-09-24 US disclosed
EP-3630985-A1 SYNTHESIS AND STRUCTURE OF HIGH POTENCY RNA THERAPEUTICS Arcturus Therapeutics, Inc. (US) 2020-04-08 EP disclosed
WO-2018222890-A1 SYNTHESIS AND STRUCTURE OF HIGH POTENCY RNA THERAPEUTICS ARCTURUS THERAPEUTICS, INC. (US) 2018-12-06 WO disclosed
WO-2018160592-A1 TRANSLATABLE MOLECULES AND SYNTHESIS THEREOF ARCTURUS THERAPEUTICS, INC. (US) 2018-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210290752-A1 COMPOSITIONS AND METHODS FOR INDUCING IMMUNE RESPONSES STING1, EIF2AK2, RNGTT PYGM 2588/4885SLC28A1 3651/4885SLC28A2 3790/4885
US-20210284974-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORNITHINE TRANSCARBAMYLASE DEFICIENCY OTC, OAT, ODC1 PYGM 2585/4885SLC28A1 453/4885SLC28A2 456/4885
US-20260015641-A1 METHODS FOR IN VITRO TRANSCRIPTION RNMT, RNGTT, POLM PYGM 714/4885SLC28A1 200/4885SLC28A2 186/4885
US-12390524-B2 Compositions and methods for inducing immune responses STING1, EIF2AK2, RNGTT PYGM 2588/4885SLC28A1 3651/4885SLC28A2 3790/4885
US-20200297634-A1 METHOD OF MAKING LIPID-ENCAPSULATED RNA NANOPARTICLES AUP1, RNGTT, LIPC PYGM 4854/4885SLC28A1 2741/4885SLC28A2 3307/4885
US-12509698-B2 Synthesis and structure of high potency RNA therapeutics IGF2BP3, SERPINC1, IGF2BP2 PYGM 3892/4885SLC28A1 3845/4885SLC28A2 3161/4885
US-20240002815-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY OTC, ODC1, OSGEP PYGM 3238/4885SLC28A1 528/4885SLC28A2 465/4885
US-20210290756-A1 CORONAVIRUS VACCINE COMPOSITIONS AND METHODS SARS1, RNGTT, STING1 PYGM 2573/4885SLC28A1 4180/4885SLC28A2 4342/4885
US-12398379-B2 Compositions and methods for treating ornithine transcarbamylase deficiency OTC, ODC1, OSGEP PYGM 3238/4885SLC28A1 528/4885SLC28A2 465/4885
US-11685906-B2 Compositions and methods for treating ornithine transcarbamylase deficiency OTC, ODC1, OSGEP PYGM 3238/4885SLC28A1 528/4885SLC28A2 465/4885
US-20260069677-A1 COMPOSITIONS AND METHODS FOR INDUCING IMMUNE RESPONSES STING1, MAVS, MYD88 PYGM 2110/4885SLC28A1 568/4885SLC28A2 400/4885
US-20260078356-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY OTC, OAT, POLRMT PYGM 1852/4885SLC28A1 449/4885SLC28A2 479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.