Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59871 | 0.87 | — | — | |
| SCHEMBL29471383 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL23320033 | 0.84 | MAOA (0.40) | MAOAMAOBTSHRCA1CA2 | |
| SCHEMBL16439994 | 0.84 | — | — | |
| Hno SCHEMBL7400293 | 0.79 | MAOA (0.42) | MAOAMAOBTSHRCA1CA2 | |
| SCHEMBL11505396 | 0.79 | LMNA (0.48) | MAOAMAOBTSHRCA1CA2 | |
| SCHEMBL11505205 | 0.79 | LMNA (0.48) | MAOAMAOBTSHRCA1CA2 | |
| SCHEMBL11505050 | 0.79 | LMNA (0.48) | MAOAMAOBTSHRCA1CA2 | |
| SCHEMBL11508366 | 0.79 | LMNA (0.48) | MAOAMAOBTSHRCA1CA2 | |
| SCHEMBL11227471 | 0.79 | LMNA (0.48) | MAOAMAOBTSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747213-B1 | NOVEL 7,7-DISUBSTITUTED DERIVATIVES OF (5H,9H)-6,8-DIOXABENZOCYCLOHEPTENE, PREPARATION METHOD THEREOF AND USE OF SAME IN THE SYNTHESIS OF NON-STEROIDAL VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-05-26 | — | — | EP | claimed |
| US-7319155-B2 | 7,7-disubstituted (5H,9H)-6,8-dioxabenzocycloheptene compounds useful in the synthesis of non-steroidal analogues of vitamin D | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-01-15 | — | — | US | claimed |
| US-20070117989-A1 | Methanesulfonic acid [7-(4-nitrophenyl)-(5H,9H)-6,8-dioxabenzocyclohepten-2-yl]methyl ester; chemical intermediates | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-05-24 | — | — | US | claimed |
| EP-1747213-A1 | NOVEL 7,7-DISUBSTITUTED DERIVATIVES OF (5H,9H)-6,8-DIOXABENZOCYCLOHEPTENE, PREPARATION METHOD THEREOF AND USE OF SAME IN THE SYNTHESIS OF NON-STEROIDAL VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2007-01-31 | — | — | EP | claimed |
| WO-2005116007-A1 | NOVEL 7,7-DISUBSTITUTED DERIVATIVES OF (5H,9H)-6,8-DIOXABENZOCYCLOHEPTENE, PREPARATION METHOD THEREOF AND USE OF SAME IN THE SYNTHESIS OF NON-STEROIDAL VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-12-08 | — | — | WO | claimed |
| WO-1992022546-A1 | SUBSTITUTED 1,5-DIHYDRO-3H-2,4-BENZODIOXEPINES AS OPTICALLY ACTIVE GLYDERALDEHYDES OR GLYCIDALDEHYDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-12-23 | — | — | WO | claimed |
| US-5162554-A | Optically active enantiomers of substituted glyceraldehydes or glycidaldehydes formed as subtituted 1,5- dihydro-3H-2,4-benzodioxepines | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-11-10 | — | — | US | claimed |
| US-12535735-B2 | Modified thioxanthone photoinitiators | LINTFIELD LIMITED (GB) | 2026-01-27 | — | — | US | disclosed |
| US-12471596-B2 | Substituted 6-membered heteroaryl piperidinyl ethanones | PI INDUSTRIES LTD. (IN) | 2025-11-18 | — | — | US | disclosed |
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20230082557-A1 | Modified Thioxanthone Photoinitiators | LINTFIELD LIMITED (GB) | 2023-03-16 | — | — | US | disclosed |
| US-20230031192-A1 | NOVEL SUBSTITUTED 6- MEMBERED HETEROARYL PIPERIDINYL ETHANONES | PI INDUSTRIES LTD. (IN) | 2023-02-02 | — | — | US | disclosed |
| US-10919872-B2 | Method for producing 2-alkylcarbonylnaphtho[2,3-b]furan-4,9-dione-related substance, and said related substance | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-02-16 | — | — | US | disclosed |
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1992022546-A1 | SUBSTITUTED 1,5-DIHYDRO-3H-2,4-BENZODIOXEPINES AS OPTICALLY ACTIVE GLYDERALDEHYDES OR GLYCIDALDEHYDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-12-23 | — | — | WO | disclosed |
| WO-1992022546-A1 | SUBSTITUTED 1,5-DIHYDRO-3H-2,4-BENZODIOXEPINES AS OPTICALLY ACTIVE GLYDERALDEHYDES OR GLYCIDALDEHYDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-12-23 | — | — | WO | disclosed |
| US-5162554-A | Optically active enantiomers of substituted glyceraldehydes or glycidaldehydes formed as subtituted 1,5- dihydro-3H-2,4-benzodioxepines | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-11-10 | — | — | US | disclosed |
| US-5162554-A | Optically active enantiomers of substituted glyceraldehydes or glycidaldehydes formed as subtituted 1,5- dihydro-3H-2,4-benzodioxepines | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-11-10 | — | — | US | disclosed |
| US-5162554-A | Optically active enantiomers of substituted glyceraldehydes or glycidaldehydes formed as subtituted 1,5- dihydro-3H-2,4-benzodioxepines | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117989-A1 | Methanesulfonic acid [7-(4-nitrophenyl)-(5H,9H)-6,8-dioxabenzocyclohepten-2-yl]methyl ester; chemical intermediates | CYP24A1, CYP2R1, VDR | MAOA 4307/4885MAOB 3390/4885TSHR 2047/4885 |
| US-20230082557-A1 | Modified Thioxanthone Photoinitiators | TPMT, PPOX, TST | MAOA 358/4885MAOB 469/4885TSHR 690/4885 |
| US-12471596-B2 | Substituted 6-membered heteroaryl piperidinyl ethanones | CCNK, CCNA1, CYP1A1 | MAOA 876/4885MAOB 1306/4885TSHR 4087/4885 |
| US-20230031192-A1 | NOVEL SUBSTITUTED 6- MEMBERED HETEROARYL PIPERIDINYL ETHANONES | CCNK, CYP1B1, CYP1A1 | MAOA 775/4885MAOB 965/4885TSHR 4023/4885 |
| US-12535735-B2 | Modified thioxanthone photoinitiators | FTO, UGT1A6, TPMT | MAOA 2290/4885MAOB 2606/4885TSHR 414/4885 |
| US-10919872-B2 | Method for producing 2-alkylcarbonylnaphtho[2,3-b]furan-4,9-dione-related substance, and said related substance | ADH1C, ADH5, ADH1A | MAOA 341/4885MAOB 127/4885TSHR 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.