SCHEMBL20970947

SCHEMBL20970947

CCCN(CC)CCc1c[nH]c2cccc(OC(C)=O)c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 4/20 0.56
HTR2A P28223 10/20 0.54
HTR6 P50406 3/20 0.50
HTR2C P28335 3/20 0.50
HTR2B P41595 3/20 0.50
MTNR1A P48039 1/20 0.48
MTNR1B P49286 1/20 0.48
HTR1D P28221 3/20 0.43
DRD1 P21728 1/20 0.43
HTR1B P28222 1/20 0.43
HTR1E P28566 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43
HTR7 P34969 1/20 0.43
DRD3 P35462 1/20 0.43
HTR5A P47898 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633078 1.00 HTR1A (0.56) HTR1AHTR2AHTR6HTR2CHTR2B
SCHEMBL20970971 0.95 HTR2A (0.52) HTR1AHTR2AHTR6HTR2CHTR2B
SCHEMBL29633123 0.95 HTR2A (0.52) HTR1AHTR2AHTR6HTR2CHTR2B
SCHEMBL4212211 0.94 HTR1A (0.63) HTR1AHTR2AHTR6HTR2CHTR2B
SCHEMBL29400822 0.94 HTR1A (0.63) HTR1AHTR2AHTR6HTR2CHTR2B
Fumaric Acid SCHEMBL30366691 0.94 HTR1A (0.50) HTR1AHTR2AHTR6HTR2CHTR2B
SCHEMBL27084985 0.90 HTR2A (0.57) HTR1AHTR2AHTR6HTR2CHTR2B
SCHEMBL27084739 0.90 HTR2A (0.57) HTR1AHTR2AHTR6HTR2CHTR2B
SCHEMBL27084894 0.89 HTR1A (0.54) HTR1AHTR2AHTR6HTR2CHTR2B
SCHEMBL31086232 0.89 HTR2A (0.56) HTR1AHTR2AHTR6HTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4615585-A1 METHODS OF USING TRAZODONE TO REVERSE THE EFFECTS OF 5-HT2A RECEPTOR AGONISTS Gilgamesh Pharmaceuticals, Inc. (US) 2025-09-17 EP claimed
US-20240390301-A1 COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS GILGAMESH PHARMACEUTICALS, INC. (US) 2024-11-28 US claimed
EP-4415710-A1 CRYSTALLINE TRYPTAMINE COMPOUNDS Caamtech, Inc. (US) 2024-08-21 EP claimed
US-20240216339-A1 METHODS OF TREATING NEUROPSYCHIATRIC DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2024-07-04 US claimed
WO-2024102458-A1 METHODS OF USING TRAZODONE TO REVERSE THE EFFECTS OF 5-HT2A RECEPTOR AGONISTS GILGAMESH PHARMACEUTICALS, INC. (US) 2024-05-16 WO claimed
WO-2023064840-A1 CRYSTALLINE TRYPTAMINE COMPOUNDS CAAMTECH, INC. (US) 2023-04-20 WO claimed
WO-2023028086-A1 COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS GILGAMESH PHARMACEUTICALS, INC. (US) 2023-03-02 WO claimed
WO-2022261263-A1 METHODS OF TREATING NEUROPSYCHIATRIC DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2022-12-15 WO claimed
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US disclosed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-10 US disclosed
US-20260060979-A1 METHOD FOR IMPROVING NEUROPLASTICITY ALTO NEUROSCIENCE INC (US) 2026-03-05 US disclosed
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-03 US disclosed
US-12497361-B2 Crystalline tryptamine compounds CAAMTECH, INC. (US) 2025-12-16 US disclosed
WO-2022115798-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE WESANA HEALTH INC. (US) 2022-06-02 WO disclosed
US-20220054402-A1 COMPOSITIONS AND METHODS FOR EXTRACTING, STABILIZING, AND MANUFACTURING STABLE DOSAGE FORMS OF PSILOCIN, PSYCHEDELIC DRUGS, ENTHEOGENS, AND MEDICINAL MUSHROOMS AS NANO-DIMENSIONAL DRUG DELIVERY STRUCTURES KAUFMAN RICHARD C (US) 2022-02-24 US disclosed
US-20220041551-A1 METHODS OF TREATING MOOD DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2022-02-10 US disclosed
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-25 US disclosed
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-11 US disclosed
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CAAMTECH, INC. 2019-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CNR1, CNR2, HTR5A HTR1A 5/4885HTR2A 6/4885HTR6 10/4885
US-20240390301-A1 COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS HTR2A, HTR2C, HTR5A HTR1A 4/4885HTR2A 1/4885HTR6 9/4885
US-20220041551-A1 METHODS OF TREATING MOOD DISORDERS GRIN2C, GRIN2A, TPH2 HTR1A 23/4885HTR2A 5/4885HTR6 13/4885
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 HTR1A 5/4885HTR2A 6/4885HTR6 3/4885
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A HTR1A 5/4885HTR2A 2/4885HTR6 10/4885
US-12497361-B2 Crystalline tryptamine compounds TPH1, HTR5A, TPH2 HTR1A 7/4885HTR2A 14/4885HTR6 11/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B HTR1A 22/4885HTR2A 19/4885HTR6 16/4885
US-20260060979-A1 METHOD FOR IMPROVING NEUROPLASTICITY NTRK2, BDNF, GRIN2A HTR1A 38/4885HTR2A 13/4885HTR6 65/4885
US-20240216339-A1 METHODS OF TREATING NEUROPSYCHIATRIC DISORDERS HCRTR2, HCRTR1, HTR2A HTR1A 9/4885HTR2A 3/4885HTR6 27/4885
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A HTR1A 5/4885HTR2A 2/4885HTR6 10/4885
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same HTR1D, HTR1A, HTR4 HTR1A 2/4885HTR2A 14/4885HTR6 8/4885
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same HTR5A, HTR1A, HTR1D HTR1A 2/4885HTR2A 16/4885HTR6 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.